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[已撤回] 5-脂氧合酶的抑制触发胰腺癌细胞凋亡。

[Retracted] Inhibition of 5‑lipoxygenase triggers apoptosis in pancreatic cancer cells.

作者信息

Zhou Guo-Xiong, Ding Xiao-Ling, Wu Sheng-Bao, Zhang Hai-Feng, Cao Wei, Qu Li-Shuai, Zhang Hong

机构信息

Department of Gastroenterology, Affliliated Hospital of Nantong University, Jiangsu, Nantong 226001, P.R. China.

出版信息

Oncol Rep. 2025 Feb;53(2). doi: 10.3892/or.2024.8853. Epub 2024 Dec 13.

DOI:10.3892/or.2024.8853
PMID:39670304
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11652959/
Abstract

Following the publication of the above paper, a concerned reader drew to the Editor's attention that Fig. 3 on p. 664, showing TUNEL assay data relating to apoptosis of the cell line under investigation in this paper, contained apparent anomalies, including repeated patternings of certain cells both within and between the data panels, such that it would have been difficult to have attributed these anomalies to coincidence. After having conducted an independent investigation in the Editorial Office, the Editor of has determined that the above paper should be retracted from the Journal on account of a lack of confidence concerning the originality and the authenticity of the data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor regrets any inconvenience that has been caused to the readership of the Journal. [Oncology Reports 33: 661‑668, 2015; DOI: 10.3892/or.2014.3650].

摘要

上述论文发表后,一位关注此事的读者提请编辑注意,第664页的图3展示了与本文所研究细胞系凋亡相关的TUNEL检测数据,其中存在明显异常,包括数据面板内和面板之间某些细胞的重复模式,以至于很难将这些异常归因于巧合。编辑部进行独立调查后,《肿瘤学报告》的编辑认定,鉴于对数据的原创性和真实性缺乏信心,上述论文应从该期刊撤回。已要求作者对这些问题作出解释,但编辑部未收到令人满意的答复。编辑对给期刊读者带来的任何不便表示歉意。[《肿瘤学报告》33: 661 - 668, 2015; DOI: 10.3892/or.2014.3650]

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