Fentiman I S, Matthews P N, Davison O W, Millis R R, Hayward J L
Br J Surg. 1985 Jan;72(1):14-6. doi: 10.1002/bjs.1800720107.
Seventy-three patients with breast cancer, treated by radical mastectomy, who subsequently developed a local skin recurrence without clinical evidence of disseminated disease, have been reviewed. There were significant differences between the survival of patients with single and multiple recurrences. Only 10 per cent of those with multiple lesions survived 5 years, and none was alive at 10 years, whereas 42 per cent of those with single lesions survived 5 years and 22 per cent were alive and well at 10 years' postrecurrence. Adequate local treatment of a single skin nodule may enable a subset of patients to survive without subsequent development of breast cancer metastases.
对73例行根治性乳房切除术且随后出现局部皮肤复发但无播散性疾病临床证据的乳腺癌患者进行了回顾性研究。单发和多发复发患者的生存率存在显著差异。多发病灶患者中只有10%存活了5年，10年后无一存活；而单发病灶患者中42%存活了5年，复发后10年有22%存活且状况良好。对单个皮肤结节进行充分的局部治疗可能使一部分患者存活，而后续不会发生乳腺癌转移。
