Zieff Gabriel, Bancks Michael P, Gabriel Kelley Pettee, Barone Gibbs Bethany, Moore Justin B, Reis Jared P, Stone Keeron, Stoner Lee
Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, United States.
School of Kinesiology, The University of British Columbia, Vancouver, BC V6T 1Z1, Canada.
Ann Behav Med. 2025 Jan 4;59(1). doi: 10.1093/abm/kaae074.
The association between sedentary behavior (SB) and cardiometabolic risk may differ by SB domain and context. Nonoccupational SB is particularly important because it is discretionary and more amenable to change. This study estimated associations of nonoccupational SB contexts with hypertension (HTN) and diabetes mellitus (DM).
A total of 3370 middle-aged adults (50.1 ± 3.6 years; 56% F) from the Coronary Artery Risk Development in Young Adults (CARDIA) study were included. Cross-sectional and 5-year prospective associations between self-report total SB and 6 context-specific SBs (television-TV, computer, transportation, phone, music, and paperwork) with HTN and DM were tested using logistic regression. Fully adjusted models controlled for sociodemographic variables, body mass index, and self-report moderate-vigorous intensity physical activity.
Prevalences of HTN and DM at baseline were 48% (1618 cases) and 10% (320 cases), respectively. Each hour per day of total-SB was cross-sectionally associated with HTN (OR: 1.03, 95% CI, 1.01-1.05) but not DM, with nonsignificant prospective associations for HTN and DM. Of the context-specific SBs, only TV-SB was significantly associated with HTN or DM. Each hour of TV-SB was cross-sectionally associated with HTN (OR: 1.09, 95% CI, 1.03-1.15) and DM (OR: 1.18, 95% CI, 1.09-1.29), and prospectively with HTN (OR: 1.14, 95% CI, 1.04-1.26) but not DM.
When comparing total-SB and the 6 context-specific SBs, TV-SB was most robustly associated with HTN. The findings were less clear for DM. Behavior change strategies that target TV-SB reduction may be effective at reducing HTN risk in middle-aged adults.
久坐行为（SB）与心血管代谢风险之间的关联可能因SB领域和背景而异。非职业性SB尤为重要，因为它是可自由支配的，且更易于改变。本研究估计了非职业性SB背景与高血压（HTN）和糖尿病（DM）之间的关联。
纳入了来自青年动脉粥样硬化风险发展研究（CARDIA）的3370名中年成年人（50.1±3.6岁；56%为女性）。使用逻辑回归测试了自我报告的总SB以及6种特定背景的SB（电视、电脑、交通、电话、音乐和文书工作）与HTN和DM之间的横断面和5年前瞻性关联。完全调整模型控制了社会人口统计学变量、体重指数和自我报告的中等强度到高强度身体活动。
基线时HTN和DM的患病率分别为48%（1618例）和10%（320例）。总SB每天每小时与HTN呈横断面关联（比值比：1.03，95%置信区间，1.01 - 1.05），但与DM无关联，HTN和DM的前瞻性关联无统计学意义。在特定背景的SB中，只有电视SB与HTN或DM显著相关。电视SB每小时与HTN呈横断面关联（比值比：1.09，95%置信区间，1.03 - 1.15）和与DM呈横断面关联（比值比：1.18，95%置信区间，1.09 - 1.29），并且前瞻性地与HTN相关（比值比：1.14，95%置信区间，1.04 - 1.26），但与DM无关联。
在比较总SB和6种特定背景的SB时，电视SB与HTN的关联最为显著。对于DM，研究结果不太明确。针对减少电视SB的行为改变策略可能对降低中年成年人的HTN风险有效。
