早发性胰腺癌：综述
Early onset pancreatic cancer: A review.
作者信息
Luo Dong, Li Yixiong, Yu Xiao, Ji Liandong, Gong Xuejun
机构信息
Department of Pancreatic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, China; Department of General, Visceral and Transplant Surgery, European Pancreas Centre, Heidelberg. University Hospital, Heidelberg, Germany.
Department of Pancreatic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, China.
出版信息
Transl Oncol. 2025 Feb;52:102239. doi: 10.1016/j.tranon.2024.102239. Epub 2024 Dec 12.
Early-onset pancreatic cancer (EOPC) is usually defined as patients with pancreatic cancer before the age of 50 years, which is relatively rare. However, the research on EOPC is somewhat obscure, and the specific clinical and molecular characteristics of this condition are debated. In this review, we discussed the differences between EOPC and late-onset pancreatic cancer (LOPC) or average-onset pancreatic cancer (AOPC) with a focus on clinical and molecular characteristics, survival outcomes and treatment to promote the diagnosis and treatment of EOPC.
早发性胰腺癌（EOPC）通常定义为50岁之前患胰腺癌的患者，这相对罕见。然而，关于EOPC的研究有些模糊，这种疾病的具体临床和分子特征存在争议。在本综述中，我们讨论了EOPC与晚发性胰腺癌（LOPC）或平均发病年龄胰腺癌（AOPC）之间的差异，重点关注临床和分子特征、生存结果及治疗，以促进EOPC的诊断和治疗。
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