Krzyzaniak Halli, Vergouwen Martina, Van Essen Darren, Nixon Curtis, McClure R Scott, Jadavji Nadeem, Moore Randy D, Rommens Kenton
From the Cumming School of Medicine, University of Calgary, Calgary, Alta. (Krzyzaniak, Vergouwen, Van Essen, Nixon); the Department of Surgery, Section of Vascular Surgery, University of Calgary, Calgary, Alta. (Krzyzaniak, Moore, Rommens); the Department of Cardiac Sciences, Section of Cardiac Surgery, University of Calgary, Calgary, Alta. (McClure); the Calgary Aortic Program, Calgary, Alta. (McClure, Moore, Rommens); the Department of Anesthesiology, Perioperative and Pain Medicine, University of Calgary, Calgary, Alta. (Nixon, Jadavji)
From the Cumming School of Medicine, University of Calgary, Calgary, Alta. (Krzyzaniak, Vergouwen, Van Essen, Nixon); the Department of Surgery, Section of Vascular Surgery, University of Calgary, Calgary, Alta. (Krzyzaniak, Moore, Rommens); the Department of Cardiac Sciences, Section of Cardiac Surgery, University of Calgary, Calgary, Alta. (McClure); the Calgary Aortic Program, Calgary, Alta. (McClure, Moore, Rommens); the Department of Anesthesiology, Perioperative and Pain Medicine, University of Calgary, Calgary, Alta. (Nixon, Jadavji).
Can J Surg. 2024 Dec 13;67(6):E389-E396. doi: 10.1503/cjs.003624. Print 2024 Nov-Dec.
Cerebrospinal fluid (CSF) drainage is used to reduce spinal cord ischemia (SCI) in patients undergoing thoracoabdominal aortic procedures. Recent literature has found high rates of complication associated with CSF drainage, which has led to changes in practice. The aim of this study was to investigate rates of CSF drain-related complications in patients undergoing a thoracoabdominal aortic procedure with perioperative placement of a CSF drain.
We conducted a single-centre retrospective cohort study. We defined major complications as intracranial hemorrhage, epidural hematoma or abscess, meningitis, and catheter retention requiring a reoperation. Minor complications assessed included drain-induced neurologic deficits, CSF leak, postdural puncture headache, asymptomatic blood in the CSF, drain failure, and catheter retention not requiring a reoperation. We recorded postoperative neurologic deficits as secondary outcomes.
There were 129 patients who met the inclusion criteria. We found 5 cases of permanent paraplegia in the overall cohort (3.9%), with only 2 occurring in the patients with prophylactic CSF drains (1.6%). There were no major CSF drain-related complications. The rate of minor complications was 17.8%. We found no association between complication rates and indication for procedure or type of operation.
The lack of major complications in this series adds to existing variability in recent literature and provides support for continued use of this adjunct for SCI prevention. Further research is required to identify the etiology of significant differences in CSF drain complication rates seen at other centres.
脑脊液引流用于降低接受胸腹主动脉手术患者的脊髓缺血(SCI)风险。近期文献发现脑脊液引流相关并发症发生率较高,这导致了实践中的改变。本研究的目的是调查在接受胸腹主动脉手术且围手术期放置脑脊液引流管的患者中脑脊液引流相关并发症的发生率。
我们进行了一项单中心回顾性队列研究。我们将主要并发症定义为颅内出血、硬膜外血肿或脓肿、脑膜炎以及需要再次手术的导管留置。评估的次要并发症包括引流管引起的神经功能缺损、脑脊液漏、硬膜穿刺后头痛、脑脊液中无症状血液、引流失败以及不需要再次手术的导管留置。我们将术后神经功能缺损记录为次要结局。
有129例患者符合纳入标准。我们在整个队列中发现5例永久性截瘫(3.9%),其中只有2例发生在预防性脑脊液引流管的患者中(1.6%)。没有与脑脊液引流相关的主要并发症。次要并发症发生率为17.8%。我们发现并发症发生率与手术指征或手术类型之间没有关联。
本系列中缺乏主要并发症,这增加了近期文献中现有的变异性,并为继续使用这种预防脊髓缺血的辅助手段提供了支持。需要进一步研究以确定其他中心所见脑脊液引流并发症发生率显著差异的病因。