Gebrye T, Jeans E, Yeowell G, Mbada C, Fatoye F
Department of Health Professions, Manchester Metropolitan University, Manchester, UK.
Orthopaedics, North Shore Hospital, Auckland, New Zealand.
Musculoskeletal Care. 2024 Dec;22(4):e70024. doi: 10.1002/msc.70024.
Carpal tunnel syndrome (CTS) is a considerable concern, impacting individual health and socio-economic factors. A systematic review and meta-analysis of CTS prevalence would offer valuable insights for healthcare planning, improving outcomes and reducing the burden on affected individuals.
In line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a meta-analysis was conducted to estimate the prevalence of CTS. Medline, CINAHL, AMED, Scopus, and Web of Science databases were searched for studies published from 1 January 2012 to 10 October 2024. The pooled prevalence rates were determined using a random effects model.
The search yielded 548 initial findings, 103 duplicate records were eliminated, and only 31 of these papers were deemed relevant for inclusion in this review. The prevalence estimates were sourced from 15 different countries, including the United States (n = 8), Saudi Arabia (n = 5), Ethiopia (n = 3), Turkey (n = 2), Iran (n = 2) and Brazil (n = 2), among others. Each of the following countries contributed one study: China, France, Germany, India, Kuwait, the United Kingdom, Korea, the Netherlands, and Sweden. In total, the included studies analysed 5,311,785 individuals, revealing a prevalence of CTS ranging from 0.003 to 0.743. The random-effects meta-analysis yielded an overall prevalence estimate of 0.144, with a 95% confidence interval (CI) of 0.067-0.282, based on 30 studies.
The prevalence estimates for CTS are notably high, highlighting the need for effective surgical management strategies. Developing and implementing these interventions is crucial to enhancing health outcomes for individuals affected by CTS.
腕管综合征（CTS）是一个值得高度关注的问题，它会影响个人健康以及社会经济因素。对CTS患病率进行系统综述和荟萃分析，将为医疗规划、改善治疗效果以及减轻受影响个体的负担提供有价值的见解。
按照系统综述和荟萃分析的首选报告项目（PRISMA）指南，进行了一项荟萃分析以估计CTS的患病率。检索了Medline、CINAHL、AMED、Scopus和科学网数据库中2012年1月1日至2024年10月10日发表的研究。使用随机效应模型确定合并患病率。
检索共得到548项初步结果，剔除了103条重复记录，其中只有31篇论文被认为与本综述相关并纳入。患病率估计值来自15个不同国家，包括美国（n = 8）、沙特阿拉伯（n = 5）、埃塞俄比亚（n = 3）、土耳其（n = 2）、伊朗（n = 2）和巴西（n = 2）等。以下每个国家各贡献了一项研究：中国、法国、德国、印度、科威特、英国、韩国、荷兰和瑞典。纳入的研究总共分析了5311785人，CTS患病率在0.003至0.743之间。基于30项研究的随机效应荟萃分析得出总体患病率估计值为0.144，95%置信区间（CI）为（0.067 - 0.282）。
CTS的患病率估计值显著偏高，凸显了有效手术管理策略的必要性。制定和实施这些干预措施对于改善CTS患者的健康状况至关重要。
