Hettich-Damm Nora, Petersen Julia, Baumkoetter Rieke, Prochaska Jürgen H, Koenig Jochem, Schuster Alexander K, Muenzel Thomas, Lackner Karl J, Wild Philipp S, Beutel Manfred
Clinic and Polyclinic for Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Preventive Cardiology and Medical Prevention, Center for Cardiology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
BMC Public Health. 2024 Dec 13;24(1):3399. doi: 10.1186/s12889-024-20945-4.
Previous studies have found adverse effects on mental health following infection with SARS-CoV-2. This study investigates whether mental health is also impaired in unknowingly infected individuals. In addition, the relevance of the severity of the infection and the time since the onset of infection were analyzed.
Data from the population-representative Gutenberg COVID-19 Study (GCS) were used (N = 2,267). SARS-CoV-2 infection was determined multimodally by self-report, throat swabs (acute infections) and antibody measurements (previous infections). Participants completed self-report questionnaires on mental health.
Neither unknowing nor knowing SARS-CoV-2 infection had an impact on mental health. However, symptom severity and previous depression or anxiety predicted higher levels of depressiveness, anxiety and somatic complaints. Our results confirm findings suggesting that the severity of the initial infection and previous mental illness, but not knowledge of the infection, are the most important predictors of negative mental health outcomes following SARS-CoV-2 infection.
The results suggest that mental health care should focus on individuals who suffer from a severe acute COVID-19 infection or have a history of mental illness.
先前的研究发现，感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）后会对心理健康产生不良影响。本研究调查在未意识到已被感染的个体中，心理健康是否也会受到损害。此外，还分析了感染严重程度和感染发病后的时间的相关性。
使用来自具有人群代表性的古登堡新冠病毒研究（GCS）的数据（N = 2267）。通过自我报告、咽拭子（急性感染）和抗体检测（既往感染）等多种方式确定SARS-CoV-2感染情况。参与者完成关于心理健康的自我报告问卷。
未意识到感染和意识到感染SARS-CoV-2均未对心理健康产生影响。然而，症状严重程度以及既往的抑郁或焦虑预示着更高水平的抑郁、焦虑和躯体不适。我们的结果证实了以下研究结果，即初始感染的严重程度和既往精神疾病是SARS-CoV-2感染后负面心理健康结果的最重要预测因素，但感染认知并非如此。
结果表明，心理保健应聚焦于患有严重急性新冠病毒感染或有精神疾病史的个体。
