Asada Tomoyuki, Simon Chad Z, Durbas Atahan, Allen Myles R J, DiSilvestro Kevin J, Hirase Takashi, Bovonratwet Patawut, Singh Nishtha, Tuma Olivia, Araghi Kasra, Subramanian Tejas, Korsun Maximilian K, Zhang Joshua, Kim Eric T, Kwas Cole T, Bay Annika, Lu Amy Z, Mai Eric, Kim Yeo Eun, Vaishnav Avani S, Dowdell James E, Sheha Evan D, Qureshi Sheeraz A, Iyer Sravisht
Hospital for Special Surgery, 535 E. 70th St, New York, NY, 10021, USA.
Weill Cornell Medical College, 1300 York Ave, New York, NY, 10065, USA.
Eur Spine J. 2025 Feb;34(2):773-781. doi: 10.1007/s00586-024-08599-7. Epub 2024 Dec 14.
This study investigates the relationship between surgical levels and coronal deformity to identify risk factors for failing to achieve a minimal clinically important difference (MCID) in the Oswestry Disability Index (ODI) following short-segment isolated decompression or fusion surgery in patients with degenerative scoliosis (DS) and concurrent lumbar canal stenosis (LCS), without severe sagittal deformity malalignment.
Patients with degenerative scoliosis who underwent 1- or 2-level lumbar isolated decompression or fusion surgery were included. Surgical level was labeled as "Cobb-related" when decompression or surgical levels spanned or were between end vertebrae, and "outside" when the operative levels did not include the end vertebrae. Logistic regression analysis was conducted to assess the factor associated with MCID achievement in ODI at 1 year postoperatively.
A total of 129 DS patients with LCS and preoperative ODI > 30 were included. At 1-year follow-up, 91 patients (70.5%) achieved MCID in ODI. No significant differences were found in demographics or overall spinal alignment between patients who did and did not achieve MCID. Logistic regression analysis revealed that Cobb-related decompression was independently associated with decreased odds of achieving MCID in ODI (adjusted Odds Ratio 0.18, 95% CI 0.42-0.79, P = 0.025).
In patients with mild to moderate coronal deformity and minimal sagittal deformity, decompression alone at or across end vertebrae significantly lowers the likelihood of achieving the MCID in ODI compared to fusion surgery, with an 84% reduction in odds. No significant difference in MCID achievement was observed between decompression and fusion surgeries outside the Cobb angle.
本研究调查手术节段与冠状面畸形之间的关系,以确定在退行性脊柱侧凸(DS)合并腰椎管狭窄(LCS)且无严重矢状面畸形失准的患者中,短节段单纯减压或融合手术后未能达到Oswestry功能障碍指数(ODI)最小临床重要差异(MCID)的风险因素。
纳入接受1或2节段腰椎单纯减压或融合手术的退行性脊柱侧凸患者。当减压或手术节段跨越或位于终椎之间时,手术节段标记为“与Cobb角相关”;当手术节段不包括终椎时,标记为“外侧”。进行逻辑回归分析,以评估术后1年ODI达到MCID的相关因素。
共纳入129例DS合并LCS且术前ODI>30的患者。在1年随访时,91例患者(70.5%)在ODI中达到MCID。达到和未达到MCID的患者在人口统计学或整体脊柱排列方面无显著差异。逻辑回归分析显示,与Cobb角相关的减压独立于ODI达到MCID的几率降低相关(调整后的优势比为0.18,95%可信区间为0.42 - 0.79,P = 0.025)。
在轻度至中度冠状面畸形和最小矢状面畸形的患者中,与融合手术相比,在终椎处或跨越终椎进行单纯减压显著降低了在ODI中达到MCID的可能性,几率降低了84%。在Cobb角外侧进行减压和融合手术之间,在达到MCID方面未观察到显著差异。