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单纯微创减压治疗 Cobb 角大于 20°的退行性脊柱侧凸的疗效改善有限:减压部位的影响。

Limited Improvement With Minimally Invasive Lumbar Decompression Alone for Degenerative Scoliosis With Cobb Angle Over 20°: The Impact of Decompression Location.

机构信息

Hospital for Special Surgery, New York, NY.

Department of Orthopaedic Surgery, University of Tsukuba, Institute of Medicine, Tsukuba, Japan.

出版信息

Spine (Phila Pa 1976). 2024 Aug 1;49(15):1037-1045. doi: 10.1097/BRS.0000000000004968. Epub 2024 Feb 20.

Abstract

STUDY DESIGN

Retrospective review of a prospectively collected multisurgeon registry.

OBJECTIVE

To evaluate the outcomes of minimally invasive (MI) decompression in patients with severe degenerative scoliosis (DS) and identify factors associated with poorer outcomes.

SUMMARY OF BACKGROUND CONTEXT

MI decompression has gained widespread acceptance as a treatment option for patients with lumbar canal stenosis and DS. However, there is a lack of research regarding the clinical outcomes and the impact of MI decompression location in patients with severe DS exhibiting a Cobb angle exceeding 20°.

MATERIALS AND METHODS

Patients who underwent MI decompression alone were included and categorized into the DS or control groups based on Cobb angle (>20°). Decompression location was labeled as "scoliosis-related" when the decompression levels were across or between end vertebrae and "outside" when the operative levels did not include the end vertebrae. The outcomes, including the Oswestry Disability Index (ODI), were compared between the propensity score-matched groups for improvement and minimal clinical importance difference (MCID) achievement at ≥1 year postoperatively. Multivariable regression analysis was conducted to identify factors contributing to the nonachievement of MCID in ODI of the DS group at the ≥1-year time point.

RESULTS

A total of 253 patients (41 DS) were included in the study. Following matching for age, sex, osteoporosis status, psoas muscle area, and preoperative ODI, the DS groups exhibited a significantly lower rate of MCID achievement in ODI (DS: 45.5% vs. control 69.0%, P =0.047). The "scoliosis-related" decompression (odds ratio: 9.9, P =0.028) was an independent factor of nonachievement of MCID in ODI within the DS group.

CONCLUSIONS

In patients with a Cobb angle >20°, lumbar decompression surgery, even in the MI approach, may result in limited improvement of disability and physical function. Caution should be exercised when determining a surgical plan, especially when decompression involves the level between or across the end vertebrae.

LEVEL OF EVIDENCE

摘要

研究设计

回顾性分析前瞻性收集的多外科医生登记处的数据。

目的

评估微创(MI)减压术治疗严重退行性脊柱侧凸(DS)患者的效果,并确定与较差结果相关的因素。

背景资料概要

MI 减压术已被广泛接受为治疗腰椎管狭窄和 DS 患者的一种治疗选择。然而,对于 Cobb 角超过 20°的严重 DS 患者,MI 减压术的临床效果以及 MI 减压术部位的影响缺乏研究。

材料和方法

纳入仅接受 MI 减压术的患者,并根据 Cobb 角(>20°)将其分为 DS 组或对照组。当减压水平跨越或位于终椎之间时,将减压部位标记为“与脊柱侧凸相关”,当手术水平不包括终椎时,标记为“外部”。比较两组患者术后 1 年以上 Oswestry 残疾指数(ODI)的改善情况和最小临床重要差异(MCID)的达标情况。采用多变量回归分析确定导致 DS 组患者在术后 1 年时 ODI 未达到 MCID 的因素。

结果

共纳入 253 例患者(41 例 DS)。在年龄、性别、骨质疏松状态、腰大肌面积和术前 ODI 匹配后,DS 组 ODI 的 MCID 达标率明显较低(DS:45.5% vs. 对照组:69.0%,P =0.047)。在 DS 组中,“与脊柱侧凸相关”的减压(比值比:9.9,P =0.028)是 ODI 未达到 MCID 的独立因素。

结论

在 Cobb 角>20°的患者中,即使采用 MI 方法,腰椎减压手术也可能导致残疾和身体功能的改善有限。在确定手术方案时应谨慎,尤其是当减压涉及终椎之间或跨越终椎时。

证据等级

3。

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