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新冠疫情期间主要病毒和细菌呼吸道病原体抗体水平的下降

Decline of Antibodies to Major Viral and Bacterial Respiratory Pathogens During the COVID-19 Pandemic.

作者信息

Lorenz Natalie, James Alex, Van Rooyen Tiaan, Paterson Aimee, Ramiah Ciara, Carlton Lauren H, Sharma Prachi, Baker Michael G, Charlewood Richard, McGregor Reuben, Moreland Nicole J

机构信息

Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.

Maurice Wilkins Centre, The University of Auckland, Auckland, New Zealand.

出版信息

J Infect Dis. 2025 Feb 4;231(1):e77-e81. doi: 10.1093/infdis/jiae611.

DOI:10.1093/infdis/jiae611
PMID:39673749
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11793024/
Abstract

Surges in infections caused by respiratory pathogens have been documented in multiple settings after relaxation of pandemic restrictions. Antibodies to major antigens from respiratory syncytial virus and group A Streptococcus waned significantly in a longitudinal adult cohort throughout the pandemic. This waning may have contributed to the pathogen-surges that followed.

摘要

在疫情限制放宽后，多个地区都记录到了呼吸道病原体引起的感染激增情况。在整个疫情期间，一个纵向研究的成年队列中，呼吸道合胞病毒和A组链球菌主要抗原的抗体显著减少。这种抗体减少可能促成了随后的病原体激增。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acd6/11793024/e702d9c69cd2/jiae611f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acd6/11793024/e702d9c69cd2/jiae611f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acd6/11793024/e702d9c69cd2/jiae611f1.jpg

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J Infect Public Health. 2024 Nov;17(11):102545. doi: 10.1016/j.jiph.2024.102545. Epub 2024 Sep 17.
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The Emergence and Impact of the M1 Lineage on Invasive Group A Streptococcus Disease in Aotearoa New Zealand.
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