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疫情后新一波浪潮背景下儿童感染的临床概况

The Clinical Profile of Pediatric Infections in the Context of a New Post-Pandemic Wave.

作者信息

Merișescu Mădălina Maria, Jugulete Gheorghiță, Dijmărescu Irina, Dragomirescu Anca Oana, Răduț Larisa Mirela

机构信息

Faculty of Dentistry, Department of Infectious Diseases, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.

National Institute for Infectious Diseases "Prof. Dr. Matei Bals", European HIV/AIDS and Infectious Diseases Academy, No. 1 Dr. Calistrat Grozovici Street, 021105 Bucharest, Romania.

出版信息

Microorganisms. 2025 May 17;13(5):1152. doi: 10.3390/microorganisms13051152.


DOI:10.3390/microorganisms13051152
PMID:40431322
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12114091/
Abstract

is an atypical bacterium with a tropism for the respiratory tract, but it can also cause numerous extrapulmonary involvements. The incidence of high rates varies in epidemiological waves, occurring at a frequency of 3-7 years. Since the end of 2023, an increase in the incidence of infection cases has been noted internationally. We conducted a retrospective study of children hospitalized and confirmed with infection in our clinic during the last two epidemiological peaks. We retrieved data from the hospital database and divided the patients into two groups, corresponding to the years 2018-2019 and 2023-2024, respectively. Fisher's exact test was used to compare the proportions. In the years 2023-2024, we observed a higher incidence of patients with respiratory failure ( = 0.032), pleural reaction ( = 0.016), and pulmonary consolidation ( = 0.016) compared to the group in the years 2018-2019. Gastrointestinal involvement was more frequent in the years 2018-2019 ( = 0.004). The incidence of other extrapulmonary complications did not show significant differences. Infection with has varied clinical manifestations. In patients with community-acquired pneumonia, even in cases of consolidation, the possibility of infection with must also be considered.

摘要

是一种对呼吸道有嗜性的非典型细菌,但它也可引起许多肺外受累情况。高发病率在流行病学波动中有所不同,每3至7年发生一次。自2023年底以来,国际上已注意到感染病例发病率有所增加。我们对在过去两个流行病学高峰期间在我们诊所住院并确诊感染的儿童进行了一项回顾性研究。我们从医院数据库中检索数据,并将患者分为两组,分别对应2018 - 2019年和2023 - 2024年。使用Fisher精确检验比较比例。与2018 - 2019年组相比,在2023 - 2024年,我们观察到呼吸衰竭患者( = 0.032)、胸膜反应患者( = 0.016)和肺实变患者( = 0.016)的发病率更高。2018 - 2019年胃肠道受累更为频繁( = 0.004)。其他肺外并发症的发病率没有显著差异。感染有多种临床表现。在社区获得性肺炎患者中,即使在实变病例中,也必须考虑感染的可能性。 (原文中部分“ = ”符号表述有误,可能影响理解,建议检查核对原文。)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0ca/12114091/b1cbb3fc4ff2/microorganisms-13-01152-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0ca/12114091/afe0e78a76fd/microorganisms-13-01152-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0ca/12114091/3e9f347968bb/microorganisms-13-01152-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0ca/12114091/1c070b9a932e/microorganisms-13-01152-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0ca/12114091/b1cbb3fc4ff2/microorganisms-13-01152-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0ca/12114091/afe0e78a76fd/microorganisms-13-01152-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0ca/12114091/3e9f347968bb/microorganisms-13-01152-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0ca/12114091/1c070b9a932e/microorganisms-13-01152-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0ca/12114091/b1cbb3fc4ff2/microorganisms-13-01152-g004.jpg

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