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Sunitinib induced glomerular thrombotic microangiopathy in a patient with refractory pancreatic neuroendocrine tumour.

作者信息

Khan Aisha, Consing Gangelhoff Margarita, Moubarak Simon, Herrmann Sandra, Nooruddin Karim, Alexander Mariam

机构信息

Nephrology, Corpus Christi Medical Center-Bay Area, Corpus Christi, Texas, USA.

Pathology, University of Wisconsin Hospitals & Clinics, Madison, Wisconsin, USA.

出版信息

J Clin Pathol. 2025 Apr 17;78(5):357-358. doi: 10.1136/jcp-2024-209851.

DOI:10.1136/jcp-2024-209851
PMID:39674583
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12015045/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/570b/12015045/baef7496f55f/jcp-78-5-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/570b/12015045/baef7496f55f/jcp-78-5-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/570b/12015045/baef7496f55f/jcp-78-5-g001.jpg

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Sunitinib induced glomerular thrombotic microangiopathy in a patient with refractory pancreatic neuroendocrine tumour.舒尼替尼在一名难治性胰腺神经内分泌肿瘤患者中诱发了肾小球血栓性微血管病。
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Sunitinib-induced thrombotic microangiopathy.舒尼替尼诱导的血栓性微血管病。
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本文引用的文献

1
Risk Factors for Severe Hypertension and Proteinuria After Treatment With Vascular Endothelial Growth Factor Signaling Pathway Inhibitors Among Patients With Cancer.癌症患者接受血管内皮生长因子信号通路抑制剂治疗后发生严重高血压和蛋白尿的危险因素
Kidney Int Rep. 2024 Mar 13;9(6):1897-1902. doi: 10.1016/j.ekir.2024.03.005. eCollection 2024 Jun.
2
An Update in Drug-Induced Thrombotic Microangiopathy.药物性血栓性微血管病的最新进展
Front Med (Lausanne). 2020 May 22;7:212. doi: 10.3389/fmed.2020.00212. eCollection 2020.
3
Thrombotic Microangiopathy and the Kidney.
血栓性微血管病与肾脏。
Clin J Am Soc Nephrol. 2018 Feb 7;13(2):300-317. doi: 10.2215/CJN.00620117. Epub 2017 Oct 17.
4
Thrombotic microangiopathy, cancer, and cancer drugs.血栓性微血管病、癌症和癌症药物。
Am J Kidney Dis. 2015 Nov;66(5):857-68. doi: 10.1053/j.ajkd.2015.02.340. Epub 2015 May 2.
5
Therapy of metastatic pancreatic neuroendocrine tumors (pNETs): recent insights and advances.转移性胰腺神经内分泌肿瘤（pNETs）的治疗：最新见解和进展。
J Gastroenterol. 2012 Sep;47(9):941-60. doi: 10.1007/s00535-012-0642-8. Epub 2012 Aug 11.
6
Biopsy-proven acute interstitial nephritis associated with the tyrosine kinase inhibitor sunitinib: a class effect?经活检证实的与酪氨酸激酶抑制剂舒尼替尼相关的急性间质性肾炎：一种类效应？
Nephrol Dial Transplant. 2009 Feb;24(2):673-5. doi: 10.1093/ndt/gfn625. Epub 2008 Nov 27.
7
VEGF inhibition and renal thrombotic microangiopathy.血管内皮生长因子抑制与肾血栓性微血管病
N Engl J Med. 2008 Mar 13;358(11):1129-36. doi: 10.1056/NEJMoa0707330.
8
A preeclampsia-like syndrome characterized by reversible hypertension and proteinuria induced by the multitargeted kinase inhibitors sunitinib and sorafenib.一种由多靶点激酶抑制剂舒尼替尼和索拉非尼诱导的，以可逆性高血压和蛋白尿为特征的子痫前期样综合征。
J Natl Cancer Inst. 2008 Feb 20;100(4):282-4. doi: 10.1093/jnci/djm311. Epub 2008 Feb 12.
9
Molecular basis for sunitinib efficacy and future clinical development.舒尼替尼疗效的分子基础及未来临床发展
Nat Rev Drug Discov. 2007 Sep;6(9):734-45. doi: 10.1038/nrd2380.
10
Renal thrombotic microangiopathy caused by anti-VEGF-antibody treatment for metastatic renal-cell carcinoma.抗血管内皮生长因子（VEGF）抗体治疗转移性肾细胞癌引起的肾血栓性微血管病。
Lancet Oncol. 2007 Feb;8(2):177-8. doi: 10.1016/S1470-2045(07)70037-2.