Shahmiri Shahab Shahabi, Pazouki Abdolreza, Jazi Amir Hossein Davarpanah, Safari Shiva, Mahjoubi Mohammad, Sheikhbahaei Erfan, Kermansaravi Mohammad
Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, Iran.
Center of Excellence of the European Branch of the International Federation for Surgery of Obesity, Hazrat-E Rasool Hospital, Tehran, Iran.
Obes Surg. 2025 Jan;35(1):102-111. doi: 10.1007/s11695-024-07618-2. Epub 2024 Dec 14.
While OAGB shows promise in the short to medium term, its long-term durability, weight trends, blood levels of metabolic factors and nutrients, and potential complications require further exploration through larger, longer-term studies. This study contributes to the growing body of evidence by reporting on the long-term outcomes of patients with severe obesity who underwent OAGB.
A retrospective study on prospectively collected data was conducted on a sample of 1917 patients who underwent OAGB between 2010 and 2019 and had a BMI ≥ 35 kg/m. The data required for the study were obtained from our national registry database of obesity surgery (INOSD).
In total, 1971 patients were included, with 1474 (74.8%) female predominance. The mean age and BMI before surgery were 40.31 ± 11.21 years (range 18 to 75 years) and 46.68 ± 6.7 kg/m (range 35-86.57 kg/m), respectively. The mean biliopancreatic limb length was 185.02 ± 15.61 cm. Our follow-up rate was 96.19% and 75.85% in 24 and 60 months after OAGB, respectively. %TWL and %EWL reached the maximum 18 months after the operation (36.49 ± 7.77, 81.54 ± 19.18, respectively). Suboptimal initial weight loss (SIWL) 2 years after surgery was 2.9%, and TWL less than 20% and EWL less than 50% were calculated at 5-year follow-up, which was 10.2% and 14.8%, respectively.
The results of this study indicate that OAGB has acceptable long-term effects on weight loss and the remission or improvement of obesity-related medical conditions.
虽然胃旁路袖状胃切除术（OAGB）在短期至中期显示出前景，但其长期耐久性、体重趋势、代谢因子和营养素的血液水平以及潜在并发症需要通过更大规模、更长期的研究进一步探索。本研究通过报告接受OAGB的重度肥胖患者的长期结局，为越来越多的证据做出了贡献。
对2010年至2019年间接受OAGB且BMI≥35kg/m²的1917例患者样本进行了一项基于前瞻性收集数据的回顾性研究。研究所需数据来自我们的国家肥胖手术登记数据库（INOSD）。
总共纳入1971例患者，其中女性占主导（1474例，占74.8%）。手术前的平均年龄和BMI分别为40.31±11.21岁（范围18至75岁）和46.68±6.7kg/m²（范围35 - 86.57kg/m²）。胆胰肢的平均长度为185.02±15.61cm。OAGB术后24个月和60个月的随访率分别为96.19%和75.85%。%TWL（总体重减轻百分比）和%EWL（多余体重减轻百分比）在术后18个月达到最大值（分别为36.49±7.77和81.54±19.18）。术后2年的次优初始体重减轻（SIWL）为2.9%，5年随访时计算得出TWL低于20%和EWL低于50%的比例分别为10.2%和14.8%。
本研究结果表明，OAGB对体重减轻以及肥胖相关疾病的缓解或改善具有可接受的长期效果。
