Makkapati Sneha, Harsha Muvva Sri, Palaniappan Raj
Apollo Hospitals, Chennai, India.
Obes Surg. 2025 Jan;35(1):216-223. doi: 10.1007/s11695-024-07624-4. Epub 2024 Dec 11.
This study aims to evaluate the long-term efficacy, safety, nutritional status, and resolution of obesity complications of patients following one-anastomosis gastric bypass (OAGB).
A retrospective observational study of patients who underwent OAGB in our center between January 2011 and December 2013 was performed.
During the study period, 152 patients underwent OAGB procedure in our center. Among them, 26 patients were lost to follow up and therefore were excluded from the data analysis. A total of 126 patients completed long-term follow-up of 10 years. The mean age of patients at baseline was 41 ± 12.5 years (range 20-68). At 10-year follow-up, mean excess weight loss (EWL) was 68.9 ± 22.8%. Mean BMI was 29.7 ± 12.9 kg/m, representing an overall BMI reduction of 10.6 kg/m. At 10-year follow-up among the 126 patients, 80% had resolution in DM, 71% had resolution in HTN, and 85% had resolution in OSA. There were no instances of severe malnutrition in the 126 patients in our study.
OAGB is an effective choice of bariatric/metabolic surgery for patients with higher BMI which provides good weight loss in terms of % TWL and % EWL without significant recurrent weight gain or inadequate weight loss with negligible nutritional deficiencies.
本研究旨在评估单吻合口胃旁路术（OAGB）患者的长期疗效、安全性、营养状况及肥胖并发症的缓解情况。
对2011年1月至2013年12月在本中心接受OAGB手术的患者进行回顾性观察研究。
在研究期间，本中心共有152例患者接受了OAGB手术。其中，26例患者失访，因此被排除在数据分析之外。共有126例患者完成了10年的长期随访。患者基线时的平均年龄为41±12.5岁（范围20 - 68岁）。在10年随访时，平均超重减轻（EWL）为68.9±22.8%。平均体重指数（BMI）为29.7±12.9kg/m²，总体BMI降低了10.6kg/m²。在126例患者的10年随访中，80%的糖尿病患者病情缓解，71%的高血压患者病情缓解，85%的阻塞性睡眠呼吸暂停患者病情缓解。本研究中的126例患者均未出现严重营养不良的情况。
对于BMI较高的患者，OAGB是一种有效的减肥/代谢手术选择，在总体体重减轻百分比（%TWL）和超重减轻百分比（%EWL）方面能实现良好的体重减轻，且无明显体重反弹或体重减轻不足的情况，营养缺乏可忽略不计。
