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脑室内出血后脑积水的机制:综述

Mechanisms of hydrocephalus after intraventricular haemorrhage: a review.

作者信息

Wu Wenchao, Li Qingsong

机构信息

Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin Medical University, No. 157, Health Care RoadHeilongjiang Province, Harbin City, Harbin, China.

出版信息

Childs Nerv Syst. 2024 Dec 15;41(1):49. doi: 10.1007/s00381-024-06711-2.

Abstract

Intraventricular haemorrhage (IVH) is bleeding within the ventricular system, which in adults is usually mainly secondary to cerebral haemorrhage and subarachnoid haemorrhage. Hydrocephalus is one of the most common complications of intraventricular haemorrhage, which is characterised by an increase in intracranial pressure due to an increased accumulation of cerebrospinal fluid within the ventricular system, and is closely related to the patient's prognosis. Surgical methods such as shunt surgery have been used to treat secondary hydrocephalus in recent years and have been effective in improving the survival and prognosis of patients with hydrocephalus. However, complications such as shunt blockage and intracranial infection are often faced after surgery. Moreover, little is known about the mechanism of hydrocephalus secondary to intraventricular haemorrhage. This review discusses the mechanisms regarding the occurrence of secondary hydrocephalus after intraventricular haemorrhage in adults in terms of blood clot obstruction, altered cerebrospinal fluid dynamics, inflammation, and blood composition.

摘要

脑室内出血(IVH)是指脑室系统内的出血,在成年人中通常主要继发于脑出血和蛛网膜下腔出血。脑积水是脑室内出血最常见的并发症之一,其特征是由于脑室系统内脑脊液积聚增加导致颅内压升高,并且与患者的预后密切相关。近年来,诸如分流手术等外科方法已被用于治疗继发性脑积水,并在改善脑积水患者的生存率和预后方面取得了成效。然而,术后常面临分流堵塞和颅内感染等并发症。此外,对于脑室内出血继发脑积水的机制了解甚少。本综述从血凝块阻塞、脑脊液动力学改变、炎症和血液成分等方面探讨了成人脑室内出血后继发性脑积水发生的机制。

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