Mancardi G L, Tabaton M, Liwnicz B H
Eur Neurol. 1985;24(1):49-52. doi: 10.1159/000115760.
The mitochondrial content of endothelial cells of cerebral cortical capillaries in patients with Alzheimer's disease and age-matched controls was calculated using stereologic methods. No morphologic abnormalities or quantitative changes in endothelial mitochondria are reported. Our findings do not support the hypothesis of a blood-brain barrier defect in Alzheimer's disease.
采用体视学方法计算阿尔茨海默病患者及年龄匹配对照组大脑皮质毛细血管内皮细胞的线粒体含量。未报告内皮线粒体存在形态学异常或数量变化。我们的研究结果不支持阿尔茨海默病存在血脑屏障缺陷的假说。
