Cao Yuan-Hao, Zhou Yi-Mai, Wang Si-Yu, Guo Jing, Cen Lu-Sha
The First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China.
Department of Dermatology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, Zhejiang Province, China.
World J Diabetes. 2024 Dec 15;15(12):2387-2393. doi: 10.4239/wjd.v15.i12.2387.
The pathogenesis of diabetic peripheral neuropathy (DPN) has not been fully elucidated, and treatment options are limited. Currently, the main strategies for treating DPN are strict glycemic control and symptomatic pain relief. In this editorial, we comment on an article by Li which suggested that modulating the gut microbiota using traditional Chinese medicine (TCM) may be a promising strategy for alleviating DPN symptoms. The regulation of the gut microbiota has received widespread attention in the study of various diseases. TCM can participate in the regulation of gut microbiota through multiple mechanisms, and this regulatory effect can alleviate the clinical symptoms of DPN. We briefly analyzed the promise of the gut microbiota in the early diagnosis, treatment, and clinical efficacy of TCM for DPN. The gut microbiota has potential value at multiple nodes in the occurrence and progression of DPN.
糖尿病周围神经病变（DPN）的发病机制尚未完全阐明，治疗选择有限。目前，治疗DPN的主要策略是严格控制血糖和缓解症状性疼痛。在这篇社论中，我们对李的一篇文章进行评论，该文章表明使用中药（TCM）调节肠道微生物群可能是缓解DPN症状的一种有前景的策略。肠道微生物群的调节在各种疾病的研究中受到广泛关注。中药可以通过多种机制参与肠道微生物群的调节，这种调节作用可以缓解DPN的临床症状。我们简要分析了肠道微生物群在DPN的早期诊断、治疗以及中药临床疗效方面的前景。肠道微生物群在DPN的发生和发展的多个节点具有潜在价值。
