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经颅直流电刺激(tDCS)联合平衡训练对帕金森病患者的影响:一项随机临床试验的研究方案

Effects of transcranial direct current stimulation (tDCS) associated with balance training in individuals with Parkinson's: Study protocol for a randomized clinical trial.

作者信息

Santos Raynara Fonseca Dos, Areas Guilherme Peixoto Tinoco, Areas Fernando Zanela da Silva, Baptista Pedro Porto Alegre, Mendonça Ayrles Silva Gonçalves Barbosa, Freire Junior Renato Campos

机构信息

Postgraduate Program in Human Movement Sciences, Federal University of Amazonas, Manaus, AM, Brazil.

Physiology Sciences Laboratory, Federal University of Amazonas, Manaus, AM, Brazil.

出版信息

MethodsX. 2024 Nov 10;13:103014. doi: 10.1016/j.mex.2024.103014. eCollection 2024 Dec.

DOI:10.1016/j.mex.2024.103014
PMID:39676837
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11638652/
Abstract

The present study aimed to investigate the effects of balance training associated with cerebellar tDCS on postural control in individuals with PD. This is a randomized clinical trial in which individuals were allocated to an experimental group (EG) or placebo group (PG), in which a conventional protocol of 10 Physiotherapy sessions for locomotor training and postural control was applied. In the EG, tDCS was applied, with a current setting of 1.5 mA for 20 min simultaneously with postural control training. In the PG, tDCS was applied in sham mode, with the same electrode positioning and the same number of sessions as the EG. The sample compared 34 individuals with PD (EG: 17; PG: 17).Cerebellar tDCS associated with balance training may help improve postural control and balance in walkers with Parkinson's Disease. The hypothesis is, if walking improve, the benefits may be accompanied by better balance and reduced fear of falling, and individuals may experience greater free-living physical activity at home and in the community.

摘要

本研究旨在探讨平衡训练联合小脑经颅直流电刺激(tDCS)对帕金森病(PD)患者姿势控制的影响。这是一项随机临床试验,将个体分为实验组(EG)或安慰剂组(PG),两组均采用10次物理治疗的常规方案进行运动训练和姿势控制。在EG组中,tDCS以1.5 mA的电流设置持续20分钟,同时进行姿势控制训练。在PG组中,tDCS采用假刺激模式,电极位置和刺激次数与EG组相同。该样本包括34例PD患者(EG组:17例;PG组:17例)。平衡训练联合小脑tDCS可能有助于改善帕金森病患者的姿势控制和步行平衡。研究假设是,如果步行能力得到改善,可能会伴随着更好的平衡能力和对跌倒恐惧的减轻,并且个体在家庭和社区中可能会有更多的自由生活体力活动。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ccd/11638652/8c326408da38/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ccd/11638652/5731ad73e006/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ccd/11638652/8c326408da38/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ccd/11638652/5731ad73e006/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ccd/11638652/8c326408da38/gr1.jpg

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Simultaneous Bilateral Frontal and Bilateral Cerebellar Transcranial Direct Current Stimulation in Treatment-Resistant Depression-Clinical Effects and Electrical Field Modelling of a Novel Electrodes Montage.
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Biomedicines. 2022 Jul 12;10(7):1681. doi: 10.3390/biomedicines10071681.
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