Patel Devansh A, Prasad Dinesh G, Patel Nandan J, Kothari Saakshi P, Thoria Alay S
General Surgery, Surat Municipal Institute of Medical Education and Research, Surat, IND.
General Surgery, Government Medical College, Surat, Surat, IND.
Cureus. 2024 Nov 13;16(11):e73633. doi: 10.7759/cureus.73633. eCollection 2024 Nov.
The occurrence of cutaneous metastasis from internal malignancies is relatively rare. Furthermore, cutaneous metastasis from gallbladder carcinoma is an infrequent phenomenon, with only a few reported cases. Here, we report a case of a 45-year-old male with cutaneous metastasis from primary gallbladder carcinoma, initially presenting solely with a scrotal lesion. The lesion was initially misdiagnosed. Later, an abdominal ultrasound performed for another purpose incidentally revealed a mass in the gallbladder, which was subsequently confirmed as gallbladder carcinoma by CT scan (computed tomography scan). Following the diagnosis of gallbladder carcinoma, an incisional biopsy of the lesion was performed due to the suspicion of cutaneous metastasis. Histopathological analyses and the immunohistochemical staining of the biopsy specimen confirmed it as metastatic adenocarcinoma. As for the neoplasm of the gallbladder, skin is a comparatively infrequent site of metastasis, with only a few recorded incidents. Clinicians, especially in regions with a higher incidence of gallbladder carcinoma, should always consider cutaneous metastasis as a differential while treating any abnormal skin lesion in patients with gallbladder carcinoma.
来自体内恶性肿瘤的皮肤转移相对少见。此外，胆囊癌的皮肤转移是一种罕见现象，仅有少数病例报道。在此，我们报告一例45岁男性原发性胆囊癌皮肤转移病例，最初仅表现为阴囊病变。该病变最初被误诊。后来，因其他目的进行的腹部超声偶然发现胆囊有肿物，随后经CT扫描（计算机断层扫描）确诊为胆囊癌。在诊断为胆囊癌后，由于怀疑皮肤转移，对病变进行了切开活检。活检标本的组织病理学分析和免疫组化染色证实为转移性腺癌。至于胆囊肿瘤，皮肤是相对少见的转移部位，仅有少数记录事件。临床医生，尤其是在胆囊癌发病率较高地区的医生，在治疗胆囊癌患者的任何异常皮肤病变时，应始终将皮肤转移作为鉴别诊断考虑。
