Bailey Regan L, MacFarlane Amanda J, Field Martha S, Tagkopoulos Ilias, Baranzini Sergio E, Edwards Kristen M, Rose Christopher J, Schork Nicholas J, Singhal Akshat, Wallace Byron C, Fisher Kelly P, Markakis Konstantinos, Stover Patrick J
Department of Nutrition, Texas A&M University, Cater-Mattil Hall, 373 Olsen Blvd Room 130, College Station, TX 77843, USA.
Institute for Advancing Health Through Agriculture, Texas A&M University, Borlaug Building, College Station, TX 77843, USA.
PNAS Nexus. 2024 Oct 15;3(12):pgae461. doi: 10.1093/pnasnexus/pgae461. eCollection 2024 Dec.
Science-informed decisions are best guided by the objective synthesis of the totality of evidence around a particular question and assessing its trustworthiness through systematic processes. However, there are major barriers and challenges that limit science-informed food and nutrition policy, practice, and guidance. First, insufficient evidence, primarily due to acquisition cost of generating high-quality data, and the complexity of the diet-disease relationship. Furthermore, the sheer number of systematic reviews needed across the entire agriculture and food value chain, and the cost and time required to conduct them, can delay the translation of science to policy. Artificial intelligence offers the opportunity to (i) better understand the complex etiology of diet-related chronic diseases, (ii) bring more precision to our understanding of the variation among individuals in the diet-chronic disease relationship, (iii) provide new types of computed data related to the efficacy and effectiveness of nutrition/food interventions in health promotion, and (iv) automate the generation of systematic reviews that support timely decisions. These advances include the acquisition and synthesis of heterogeneous and multimodal datasets. This perspective summarizes a meeting convened at the National Academy of Sciences, Engineering, and Medicine. The purpose of the meeting was to examine the current state and future potential of artificial intelligence in generating new types of computed data as well as automating the generation of systematic reviews to support evidence-based food and nutrition policy, practice, and guidance.
基于科学的决策最好以围绕特定问题的全部证据的客观综合为指导,并通过系统的流程评估其可信度。然而,存在一些重大障碍和挑战限制了基于科学的食品与营养政策、实践及指导。首先,证据不足,主要是由于生成高质量数据的获取成本以及饮食与疾病关系的复杂性。此外,整个农业和食品价值链需要进行大量的系统评价,以及开展这些评价所需的成本和时间,可能会延迟科学向政策的转化。人工智能提供了以下机会:(i)更好地理解与饮食相关的慢性病的复杂病因;(ii)使我们对饮食与慢性病关系中个体差异的理解更加精确;(iii)提供与营养/食品干预促进健康的功效和效果相关的新型计算数据;(iv)自动生成支持及时决策的系统评价。这些进展包括获取和综合异质和多模式数据集。本观点总结了在美国国家科学院、工程院和医学院召开的一次会议。会议的目的是探讨人工智能在生成新型计算数据以及自动生成系统评价以支持基于证据的食品与营养政策、实践及指导方面的现状和未来潜力。