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甲基纤维素处理的受辐照小鼠的内源性脾集落与巨核细胞生成

Endogenous splenic colonies and megakaryopoiesis in methylcellulose treated irradiated mice.

作者信息

Bernabei P A, Di Lollo S, Saccardi R, Arganini L, Pecoraro A, Rossi Ferrini P

出版信息

Experientia. 1985 Jan 15;41(1):97-9. doi: 10.1007/BF02005895.

DOI:10.1007/BF02005895
PMID:3967747
Abstract

Endogenous splenic colonies are increased in methylcellulose-treated irradiated mice, 10 days after sublethal irradiation (450 R). The spleen shows an enhancement of megakaryopoiesis, especially localized around foam-cell foci. This suggests that the macrophage system, activated through phagocytic activity against methylcellulose, affects megakaryopoiesis by a microenvironmental mechanism.

摘要

在接受亚致死剂量照射(450拉德)10天后,甲基纤维素处理的受照射小鼠体内的内源性脾集落数量增加。脾脏显示巨核细胞生成增强,尤其集中在泡沫细胞灶周围。这表明,通过对甲基纤维素的吞噬活性激活的巨噬细胞系统,通过微环境机制影响巨核细胞生成。

相似文献

1
Endogenous splenic colonies and megakaryopoiesis in methylcellulose treated irradiated mice.甲基纤维素处理的受辐照小鼠的内源性脾集落与巨核细胞生成
Experientia. 1985 Jan 15;41(1):97-9. doi: 10.1007/BF02005895.
2
Effect of methylcellulose injection on murine hematopoiesis.甲基纤维素注射对小鼠造血功能的影响。
Am J Physiol. 1977 Aug;233(2):H234-9. doi: 10.1152/ajpheart.1977.233.2.H234.
3
[Differential radiation susceptibility of endogenous precursor cells forming "early" and "late" hematopoietic foci in the spleen of mice].[小鼠脾脏中形成“早期”和“晚期”造血灶的内源性前体细胞的辐射敏感性差异]
Radiobiologiia. 1989 May-Jun;29(3):315-20.
4
Regeneration of murine megakaryocytopoiesis and the hematopoietic inductive microenvironment after sublethal whole body irradiation by treatment with an anabolic steroid.用合成代谢类固醇治疗亚致死性全身照射后小鼠巨核细胞生成和造血诱导微环境的再生
Acta Haematol. 1985;73(2):80-5. doi: 10.1159/000206285.
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Effect of porphyrins on the hematopoietic recovery of mice treated with gamma-radiation.卟啉对受γ射线照射小鼠造血恢复的影响。
Immunopharmacol Immunotoxicol. 1994 Feb;16(1):55-70. doi: 10.3109/08923979409029900.
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[Correlation of spleen colony formation and changes in spleen weight during its recovery in irradiated mice].[照射小鼠脾脏恢复过程中脾集落形成与脾脏重量变化的相关性]
Radiobiologiia. 1983 May-Jun;23(3):398-401.
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Role of the microenvironment on hematopoiesis. I. Stem cell differentiation into granulocytic and megakaryocytic cell lineage.微环境在造血过程中的作用。I. 干细胞向粒细胞和巨核细胞谱系的分化。
J Lab Clin Med. 1989 Oct;114(4):378-81.
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Synergistic effects of interleukin 3 and interleukin 11 on murine megakaryopoiesis in serum-free culture.
Exp Hematol. 1992 Sep;20(8):1011-6.
9
Kinetics of the development of methylcellulose-induced hepatic hematopoiesis in adult mice.成年小鼠中甲基纤维素诱导的肝脏造血发育动力学
Blood. 1978 Apr;51(4):611-22.
10
Factors influencing hematopoietic spleen colony formation in irradiated mice. 3. The effect of repetitive irradiation upon proliferative ability of colony-forming cells.影响受辐照小鼠造血脾集落形成的因素。3. 重复辐照对集落形成细胞增殖能力的影响。
J Exp Med. 1967 Nov 1;126(5):871-80. doi: 10.1084/jem.126.5.871.

本文引用的文献

1
A "DIRECT-COLORING" THIOCHOLINE METHOD FOR CHOLINESTERASES.一种用于胆碱酯酶的“直接显色”硫代胆碱法。
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2
The effects of methyl cellulose in rats with special reference to splenomegaly, anaemia and the problem of hypersplenism.甲基纤维素对大鼠的影响,特别涉及脾肿大、贫血及脾功能亢进问题。
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6
Effects of bacterial endotoxin on the occurrence of spleen colonies in irradiated mice.细菌内毒素对受辐照小鼠脾集落形成的影响。
Radiat Res. 1966 Mar;27(3):369-74.
7
Stimulation of thrombocytopoiesis in irradiated mice.照射小鼠中血小板生成的刺激。
Blood. 1970 Jun;35(6):783-92.
8
Enhancement of the recovery of hemopoietic system with carbon particles in irradiated mice.碳颗粒对受辐照小鼠造血系统恢复的促进作用
Radiat Res. 1973 Dec;56(3):494-506.
9
Reticuloendothelial system blockade as an effective method of radioprotection.网状内皮系统阻断作为一种有效的辐射防护方法。
Experientia. 1975 Jan 15;31(1):112-3. doi: 10.1007/BF01924708.
10
Effect of methylcellulose injection on murine hematopoiesis.甲基纤维素注射对小鼠造血功能的影响。
Am J Physiol. 1977 Aug;233(2):H234-9. doi: 10.1152/ajpheart.1977.233.2.H234.