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营养失调与营养相关病症:系统性硬化症中一个被低估的临床问题。

Nutritional disorders and nutrition-related conditions: an underestimated clinical problem in systemic sclerosis.

作者信息

Wojteczek Anna, Chmielewski Michał, Zdrojewski Zbigniew

机构信息

Department of Rheumatology, Clinical Immunology, Geriatrics and Internal Medicine, Medical University of Gdansk, Poland.

出版信息

Reumatologia. 2024;62(5):368-380. doi: 10.5114/reum/194035. Epub 2024 Nov 9.

DOI:10.5114/reum/194035
PMID:39677874
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11635625/
Abstract

Nutritional disorders are significant but often underestimated complications in patients with systemic sclerosis (SSc). The most prevalent nutritional disorders in SSc are malnutrition, affecting up to 62.5% of patients, and sarcopenia, with a frequency of up to 42%. Thus, clinical vigilance is recommended for the detection of eating disorders in SSc patients, particularly those with gastrointestinal involvement, cardiopulmonary complications, an advanced disease stage, and high disease activity. Nutritional treatment should be carefully tailored to the patients' clinical condition to ensure that it effectively addresses their specific needs. Studies focusing on enteral nutrition in SSc patients demonstrate its effectiveness in stabilizing or improving nutritional status in malnourished patients. In severe cases, parenteral nutrition offers viable options to support patient health. The findings highlight the importance of early nutritional assessment and intervention in improving patient outcomes and suggest that individualized nutritional therapy can be a critical component of comprehensive care for SSc patients.

摘要

营养障碍是系统性硬化症(SSc)患者中显著但常被低估的并发症。SSc中最常见的营养障碍是营养不良,影响高达62.5%的患者,以及肌肉减少症,发生率高达42%。因此,建议临床保持警惕,以检测SSc患者的饮食障碍,特别是那些有胃肠道受累、心肺并发症、疾病晚期和高疾病活动度的患者。营养治疗应根据患者的临床状况进行精心调整,以确保有效满足其特定需求。针对SSc患者肠内营养的研究表明,它在稳定或改善营养不良患者的营养状况方面是有效的。在严重情况下,肠外营养为支持患者健康提供了可行的选择。这些发现强调了早期营养评估和干预对改善患者预后的重要性,并表明个体化营养治疗可能是SSc患者综合护理的关键组成部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60e8/11635625/c922eaef7488/RU-62-194035-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60e8/11635625/7ad52eb5e56f/RU-62-194035-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60e8/11635625/c922eaef7488/RU-62-194035-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60e8/11635625/7ad52eb5e56f/RU-62-194035-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60e8/11635625/c922eaef7488/RU-62-194035-g002.jpg

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本文引用的文献

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High-Protein Nutritional Supplements Improve Nutritional Status in Malnourished Patients with Systemic Sclerosis.高蛋白营养补充剂可改善系统性硬化症营养不良患者的营养状况。
Nutrients. 2024 Aug 9;16(16):2622. doi: 10.3390/nu16162622.
2
Frequency and implications of malnutrition in systemic sclerosis.系统性硬化症中营养不良的发生率及影响
Rheumatology (Oxford). 2025 Mar 1;64(3):1251-1260. doi: 10.1093/rheumatology/keae209.
3
High prevalence of malnutrition in systemic sclerosis: Results from a French monocentric cross-sectional study.
系统性硬化症中营养不良的高患病率:一项法国单中心横断面研究的结果
Nutrition. 2023 Dec;116:112171. doi: 10.1016/j.nut.2023.112171. Epub 2023 Jul 27.
4
Evaluation of Albumin, Transferrin and Transthyretin in Inflammatory Bowel Disease Patients as Disease Activity and Nutritional Status Biomarkers.评估炎症性肠病患者的白蛋白、转铁蛋白和甲状腺素结合前白蛋白作为疾病活动和营养状况的生物标志物。
Nutrients. 2023 Aug 7;15(15):3479. doi: 10.3390/nu15153479.
5
GLIM-diagnosed malnutrition predicts mortality and risk of hospitalization in systemic sclerosis: A retrospective study.GLIM诊断的营养不良可预测系统性硬化症的死亡率和住院风险:一项回顾性研究。
Eur J Intern Med. 2023 Nov;117:103-110. doi: 10.1016/j.ejim.2023.07.017. Epub 2023 Jul 22.
6
Progressive Systemic Sclerosis With Negative Antinuclear Antibodies and Absence of Raynaud's Phenomenon: A Case Report and Literature Review.抗核抗体阴性且无雷诺现象的进行性系统性硬化症:一例报告及文献综述
Cureus. 2023 Mar 1;15(3):e35663. doi: 10.7759/cureus.35663. eCollection 2023 Mar.
7
Long-term home parenteral nutrition in systemic sclerosis-related intestinal failure is feasible but unveils occult cardiac disease.系统性硬皮病相关肠衰竭患者行长期家庭肠外营养是可行的,但会引发隐匿性心脏病。
Nutrition. 2023 Jun;110:112009. doi: 10.1016/j.nut.2023.112009. Epub 2023 Feb 23.
8
Phase angle, nutritional status, and mortality in systemic sclerosis: An exploratory pilot study.系统性硬化症中的相位角、营养状况与死亡率:一项探索性初步研究。
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Sci Rep. 2022 Oct 28;12(1):18198. doi: 10.1038/s41598-022-21914-w.