Michelmann H W, Mettler L
Fertil Steril. 1985 Feb;43(2):320-2. doi: 10.1016/s0015-0282(16)48394-9.
The chromosome analysis of undivided oocytes and polyploid embryos within a human in vitro fertilization and embryo replacement program offers a unique opportunity to develop correlations between a successful or unsuccessful fertilization and the maturity of the oocytes or the quality of the sperm. Furthermore, it provides information concerning the origin of chromosomal defects.