Castle Laurence, Andreassen Monica, Aquilina Gabriele, Bastos Maria Lourdes, Boon Polly, Fallico Biagio, FitzGerald Reginald, Frutos Fernandez Maria Jose, Grasl-Kraupp Bettina, Gundert-Remy Ursula, Gürtler Rainer, Houdeau Eric, Kurek Marcin, Louro Henriqueta, Morales Patricia, Passamonti Sabina, Barat Baviera José Manuel, Leblanc Jean-Charles, Tard Alexandra, Vermeiren Sam, Zakidou Panagiota, Ruggeri Laura
EFSA J. 2024 Dec 13;22(12):e9140. doi: 10.2903/j.efsa.2024.9140. eCollection 2024 Dec.
The EFSA Panel on Food Additives and Flavourings (FAF Panel) evaluated the safety of the extension of uses of quillaia extract (E 999) as a food additive in food supplements supplied in a solid or liquid form, excluding food supplements for infants and young children. Quillaia extract (E 999) was re-evaluated in 2019 by the EFSA FAF Panel, which derived an acceptable daily intake (ADI) of 3 mg saponins/kg bw per day for E 999, while in 2024 a follow-up of the re-evaluation was published by the FAF Panel, recommending some modifications of the existing EU specifications for quillaia extract (E 999). Currently, quillaia extract (E 999) is authorised in two food categories (FCs) i.e. FC 4.1.4 'Flavoured drinks' and FC 14.2.3 'Cider and perry' (excluding ). A 'food supplements consumers only' scenario was calculated for this opinion considering the proposed extension of uses, together with the current authorised uses at both the maximum permitted level (MPLs) and the typical reported use levels of quillaia extract (E 999) at the time of the 2019 re-evaluation. The Panel concluded that the exposure estimates using the typical reported use levels for the currently authorised food categories and considering the proposed extension of uses for E 999 in FC 17.1 'Food supplements supplied in a solid form, excluding food supplement for infants and young children' and FC 17.2 'Food supplements supplied in a liquid form, excluding food supplement for infants and young children', if authorised, would not result in an exceedance of the ADI in any population group.
欧洲食品安全局食品添加剂和调味剂专家委员会（FAF 专家委员会）评估了皂树皮提取物（E 999）作为食品添加剂在固体或液体形式的食品补充剂（不包括婴幼儿食品补充剂）中扩大使用范围的安全性。2019 年，欧洲食品安全局 FAF 专家委员会对皂树皮提取物（E 999）进行了重新评估，得出 E 999 的每日允许摄入量（ADI）为 3 毫克皂苷/千克体重/天，而在 2024 年，FAF 专家委员会发布了重新评估后的跟进报告，建议对欧盟现行的皂树皮提取物（E 999）规范进行一些修改。目前，皂树皮提取物（E 999）被批准用于两个食品类别，即食品类别 4.1.4“调味饮料”和食品类别 14.2.3“苹果酒和梨酒”（不包括……）。针对本意见，考虑到拟议的使用范围扩大，以及在 2019 年重新评估时皂树皮提取物（E 999）在最大允许水平（MPLs）和典型报告使用水平下的现行批准用途，计算了“仅针对食品补充剂消费者”的情况。专家委员会得出结论，对于目前批准的食品类别，使用典型报告使用水平，并考虑在食品类别 17.1“固体形式的食品补充剂，不包括婴幼儿食品补充剂”和食品类别 17.2“液体形式的食品补充剂，不包括婴幼儿食品补充剂”中拟议的 E 999 使用范围扩大（如获批准），在任何人群中都不会导致超过每日允许摄入量。
