Alrashdan Fatima, Woods Joshua E, Chen Ellie C, Tan Wendy, Yu Zhanghao, Wang Wei, John Mathews, Jaworski Lukas, Bernard Drew, Post Allison, Moctezuma-Ramirez Angel, Elgalad Abdelmotagaly, Yang Kaiyuan, Razavi Mehdi, Robinson Jacob T
Department of Electrical and Computer Engineering, Rice University, 6100 Main St, Houston, TX, 77005.
Texas Heart Institute, Houston, TX, USA.
Res Sq. 2024 Dec 5:rs.3.rs-5463005. doi: 10.21203/rs.3.rs-5463005/v1.
Wireless communication technologies for bioelectronic implants enable remote monitoring for diagnosis and adaptive therapeutic intervention without the constraints of wired connections. However, wireless data uplink from millimeter-scale devices deep in the body struggles to achieve low power consumption while maintaining large misalignment tolerances. Here, we report a passive wireless backscatter communication system based on magnetoelectric transducers that consumes less than 0.3 pJ/bit and achieves less than 1E-6 bit error rate at a distance of 55 mm while tolerating a misalignment of 10 mm. Using this robust data uplink, we designed a wireless cardiac sensing node that can transmit electrocardiogram signals from the beating heart surface of a porcine model to a custom external transceiver using the magnetoelectric backscatter uplink. This reliable, near-zero-power communication method provides opportunities for next-generation bioelectronics to feature real-time physiological monitoring and closed-loop therapies while maintaining a small form factor and low power consumption.
用于生物电子植入物的无线通信技术能够实现远程监测，以进行诊断和自适应治疗干预，而不受有线连接的限制。然而，来自体内深处毫米级设备的无线数据上行链路在保持较大的对准误差容限的同时，难以实现低功耗。在此，我们报告了一种基于磁电换能器的无源无线反向散射通信系统，该系统每比特功耗低于0.3 pJ，在55 mm的距离上实现了低于1E-6的误码率，同时能够容忍10 mm的对准误差。利用这种强大的数据上行链路，我们设计了一种无线心脏传感节点，该节点可以使用磁电反向散射上行链路将猪模型跳动心脏表面的心电图信号传输到定制的外部收发器。这种可靠的、近乎零功耗的通信方法为下一代生物电子学提供了机会，使其能够在保持小尺寸和低功耗的同时，实现实时生理监测和闭环治疗。
