Dong Futian
National Institute of Health Data Science at Nanjing Normal University Nanjing, Jiangsu, China.
Am J Transl Res. 2024 Nov 25;16(11):7200-7204. doi: 10.62347/WKWE7595. eCollection 2024.
Bioinformatic materials science integrates medical science, materials science, informatics, and other disciplines, aiming to maintain the balance of tissues and organs in the human body. This paper explores the relationship between structural information and the structures synthesized through regulated gene expression. Specifically, it describes the transformation of information into substances via biological structural systems, using mathematical formulas to develop bioinformatic materials. These materials have applications in medical treatments, functional foods for preventive healthcare, and cosmetic products for health maintenance. Notably, bioinformatic materials have been applied in treating acromegaly, a rare and life-threatening disease of unknown etiology, and have improved the neurofilament light chain (NFL) index and typical symptoms of Amyotrophic Lateral Sclerosis (ALS). In summary, bioinformatic materials science holds potential for enhancing human health and contributing to advances in medicine.
生物信息材料科学融合了医学、材料科学、信息学和其他学科,旨在维持人体组织和器官的平衡。本文探讨了结构信息与通过调控基因表达合成的结构之间的关系。具体而言,它描述了信息通过生物结构系统转化为物质的过程,利用数学公式开发生物信息材料。这些材料在医学治疗、预防性保健功能食品和健康维护化妆品中都有应用。值得注意的是,生物信息材料已被应用于治疗肢端肥大症(一种病因不明的罕见且危及生命的疾病),并改善了肌萎缩侧索硬化症(ALS)的神经丝轻链(NFL)指数和典型症状。总之,生物信息材料科学在促进人类健康和推动医学进步方面具有潜力。