Wang Wei-Qun, Sun Hong, Shen Dan, Lin Long, Yan Wei-Chao
Department of Pediatrics, Zhejiang Provincial Integrated Chinese and Western Medicine Hospital Hangzhou 310003, Zhejiang, China.
Am J Transl Res. 2024 Nov 15;16(11):6841-6845. doi: 10.62347/TCOH9399. eCollection 2024.
Eosinophilic gastroenteritis (EGE) is an inflammatory disease characterized by a significant increase in eosinophils. EGE itself is rare, and cases with clinical manifestations of hemorrhagic ascites are even rarer, which undoubtedly increases the risk of misdiagnosis. Given this, this study reports a rare case of pediatric EGE presenting with paroxysmal abdominal pain without apparent cause, accompanied by acute tonsillitis and mesenteric lymphadenitis, suggesting a possible intestinal infection. Following diagnostic evaluations, including abdominal ultrasound, abdominal computed tomography (CT), ascites sediment smear, bone marrow aspirate smear, and gastroscopic pathology, the child was diagnosed with EGE. Initial intravenous treatment with Ceftriaxone Sodium (Rocephin) didn't alleviate abdominal pain, and ascites gradually increased. After confirming EGE, the patient was given oral anti-inflammatory and anti-allergic treatment with Singulair and cetirizine tablets, as well as anti-inflammatory treatment with prednisone tablets. This case report will provide valuable insights into the diagnosis and treatment of EGE.
嗜酸性粒细胞性胃肠炎（EGE）是一种以嗜酸性粒细胞显著增多为特征的炎症性疾病。EGE本身较为罕见，而具有出血性腹水临床表现的病例更为罕见，这无疑增加了误诊的风险。鉴于此，本研究报告了一例罕见的儿童EGE病例，该病例表现为无明显诱因的阵发性腹痛，伴有急性扁桃体炎和肠系膜淋巴结炎，提示可能存在肠道感染。经过包括腹部超声、腹部计算机断层扫描（CT）、腹水沉渣涂片、骨髓穿刺涂片和胃镜病理检查在内的诊断评估，该患儿被诊断为EGE。最初使用头孢曲松钠（罗氏芬）进行静脉治疗未能缓解腹痛，且腹水逐渐增多。确诊EGE后，给予患者口服孟鲁司特钠咀嚼片（顺尔宁）和西替利嗪片进行抗炎和抗过敏治疗，以及口服泼尼松片进行抗炎治疗。本病例报告将为EGE的诊断和治疗提供有价值的见解。
