Weng Yuesong, Wang Longjian, Huang Jianqiang, Cai Lijun
Department of Orthopedics and Traumatology, Linhai Hospital of Traditional Chinese Medicine Linhai 317000, Zhejiang, China.
Department of Orthopedics and Traumatology, Hangzhou Xiaoshan District Orthopedics Hospital of Traditional Chinese Medicine Hangzhou 311261, Zhejiang, China.
Am J Transl Res. 2024 Nov 15;16(11):6972-6979. doi: 10.62347/WBBN6996. eCollection 2024.
To investigate the predictive factors for new fractures in adjacent vertebrae after percutaneous vertebroplasty for osteoporotic vertebral compression fractures, thus providing new insights for clinical practice.
A total of 124 patients were retrospectively included in this study. Based on the presence of new vertebral compression fractures in adjacent vertebrae postoperatively, patients were divided into a non-fracture group and a new-fracture group. Data collected included the amount of bone cement injected into a single vertebral body, postoperative bone cement leakage into the intervertebral disc, the recovery rate of anterior vertebral height, and non-surgical factors such as age, gender, duration of postoperative chest and waist circumference, bone mineral density, the number of preoperative vertebral fractures, and the presence of fissure-like changes in the vertebral body. One-way ANOVA and chi-square tests were used to analyze the correlation between these factors and secondary fractures in adjacent vertebrae. Logistic regression analysis was performed to identify the main risk factors.
Univariate analysis found that the amount of bone cement injected, the recovery rate of anterior vertebral height, the duration of chest and waist circumference, and bone mineral density were associated with new fractures in adjacent vertebrae (all P < 0.05). Logistic regression analysis showed that the recovery rate of anterior vertebral height and bone mineral density were the main risk factors for new fractures in adjacent vertebrae.
Several factors are associated with new fractures in adjacent vertebrae after percutaneous vertebroplasty for osteoporotic vertebral compression fractures. The recovery rate of anterior vertebral height and bone mineral density are the primary risk factors.
探讨经皮椎体成形术治疗骨质疏松性椎体压缩骨折后相邻椎体新发骨折的预测因素，为临床实践提供新的见解。
本研究回顾性纳入了124例患者。根据术后相邻椎体是否出现新发椎体压缩骨折，将患者分为无骨折组和新发骨折组。收集的数据包括注入单个椎体的骨水泥量、术后骨水泥渗漏至椎间盘的情况、椎体前缘高度恢复率，以及年龄、性别、术后胸腰围持续时间、骨密度、术前椎体骨折数量、椎体是否存在裂隙样改变等非手术因素。采用单因素方差分析和卡方检验分析这些因素与相邻椎体二次骨折之间的相关性。进行Logistic回归分析以确定主要危险因素。
单因素分析发现，注入骨水泥量、椎体前缘高度恢复率、胸腰围持续时间和骨密度与相邻椎体新发骨折有关（均P<0.05）。Logistic回归分析表明，椎体前缘高度恢复率和骨密度是相邻椎体新发骨折的主要危险因素。
经皮椎体成形术治疗骨质疏松性椎体压缩骨折后，有几个因素与相邻椎体新发骨折有关。椎体前缘高度恢复率和骨密度是主要危险因素。
