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多发性回肠和结肠狭窄：总是克罗恩病吗？

Multiple Ileal and Colonic Stenoses: Is It Always Crohn's Disease?

作者信息

Bencardino Sarah, Allocca Mariangela, Furfaro Federica, D'Amico Ferdinando, Parigi Tommaso Lorenzo, Danese Silvio, Zilli Alessandra

机构信息

Department of Gastroenterology and Endoscopy, IRCCS Ospedale San Raffaele and Vita-Salute San Raffaele University, Milan, Italy.

出版信息

J Crohns Colitis. 2025 May 8;19(5). doi: 10.1093/ecco-jcc/jjae174.

DOI:10.1093/ecco-jcc/jjae174
PMID:39679549
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12087567/
Abstract

A 62-year-old woman presented with multiple ileal and colonic stenoses, initially suspected to be Crohn's disease. Despite unremarkable endoscopic biopsies, surgery was performed due to clinical deterioration, and histological analysis confirmed the presence of metastatic breast cancer. This case highlights the importance of considering metastatic disease in the differential diagnosis of gastrointestinal (GI) strictures, particularly when inflammatory bowel disease markers are inconclusive or marginal. Clinicians should be aware of the potential for breast cancer to metastasize to the GI tract, which may present with symptoms mimicking primary GI diseases.

摘要

一名62岁女性出现多处回肠和结肠狭窄，最初怀疑是克罗恩病。尽管内镜活检结果无异常，但由于临床病情恶化仍进行了手术，组织学分析证实存在转移性乳腺癌。该病例强调了在胃肠道（GI）狭窄的鉴别诊断中考虑转移性疾病的重要性，特别是当炎症性肠病标志物不确定或不明显时。临床医生应意识到乳腺癌转移至胃肠道的可能性，其可能表现出类似原发性胃肠道疾病的症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d177/12087567/568fcae174fd/jjae174_fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d177/12087567/966c836baf22/jjae174_fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d177/12087567/a619066c9720/jjae174_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d177/12087567/eb2977983ec9/jjae174_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d177/12087567/8efb22867fca/jjae174_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d177/12087567/987661e1669c/jjae174_fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d177/12087567/723933b0f939/jjae174_fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d177/12087567/568fcae174fd/jjae174_fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d177/12087567/966c836baf22/jjae174_fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d177/12087567/a619066c9720/jjae174_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d177/12087567/eb2977983ec9/jjae174_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d177/12087567/8efb22867fca/jjae174_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d177/12087567/987661e1669c/jjae174_fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d177/12087567/723933b0f939/jjae174_fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d177/12087567/568fcae174fd/jjae174_fig6.jpg

相似文献

[1]
Multiple Ileal and Colonic Stenoses: Is It Always Crohn's Disease?

J Crohns Colitis. 2025-5-8

[2]
[The radical surgical treatment of Crohn's disease of the large intestine complicated by rectal stenosis and chronic intestinal obstruction].

Vestn Khir Im I I Grek. 1992-4

[3]
Crohn's disease complicated by multiple stenoses and internal fistulas clinically mimicking small bowel endometriosis.

World J Gastroenterol. 2008-1-7

[4]
Recurrent Ileal Subocclusion Related to Multiple Polyps and Misdiagnosed as Crohn's Disease.

Clin Gastroenterol Hepatol. 2017-7

[5]
Ganglioneuromatosis: an unusual cause of ileal stricture mimicking Crohn's disease.

Dig Dis Sci. 2007-8

[6]
Ileocolonic tuberculosis clinically, endoscopically, and radiologically mimicking Crohn's disease: disseminated infection after treatment with infliximab.

J Crohns Colitis. 2014-6

[7]
Diagnostic and therapeutic yield of push-and-pull enteroscopy for symptomatic small bowel Crohn's disease strictures.

Eur J Gastroenterol Hepatol. 2007-7

[8]
[Value of contrast-enhanced MR enterography in pediatric Crohn's disease: preliminary study].

J Radiol. 2005-11

[9]
Small bowel obstruction by a primary phytobezoar in Crohn's disease.

Am Surg. 2009-1

[10]
[Severe lower digestive hemorrhage in Crohn's disease].

Gastroenterol Hepatol. 1999-1

本文引用的文献

[1]
Cross-sectional imaging of mimics of inflammatory bowel disease: not everything is Crohn's disease or ulcerative colitis.

Abdom Radiol (NY). 2025-1

[2]
Cytomegalovirus colitis as intestinal obstruction in an immunocompetent adolescent: a case report and literature review.

BMC Infect Dis. 2024-4-1

[3]
Endometriosis as an Uncommon Cause of Intestinal Obstruction-A Comprehensive Literature Review.

J Clin Med. 2023-10-6

[4]
Evidence-based approach to diagnosis and management of abdominal tuberculosis.

Indian J Gastroenterol. 2023-2

[5]
Imaging of intestinal vasculitis focusing on MR and CT enterography: a two-way street between radiologic findings and clinical data.

Insights Imaging. 2022-9-4

[6]
Intestinal amyloidosis: Clinical manifestations and diagnostic challenge.

Adv Clin Exp Med. 2021-5

[7]
ECCO-ESGAR Guideline for Diagnostic Assessment in IBD Part 1: Initial diagnosis, monitoring of known IBD, detection of complications.

J Crohns Colitis. 2019-2-1

[8]
Clinical features of chronic enteropathy associated with SLCO2A1 gene: a new entity clinically distinct from Crohn's disease.

J Gastroenterol. 2018-1-8

[9]
Imaging of Uncommon Causes of Large-Bowel Obstruction.

AJR Am J Roentgenol. 2017-11

[10]
Lobular Metastatic Breast Cancer Patients With Gastrointestinal Involvement: Features and Outcomes.

Clin Breast Cancer. 2017-7-10

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