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多发性回肠和结肠狭窄:总是克罗恩病吗?

Multiple Ileal and Colonic Stenoses: Is It Always Crohn's Disease?

作者信息

Bencardino Sarah, Allocca Mariangela, Furfaro Federica, D'Amico Ferdinando, Parigi Tommaso Lorenzo, Danese Silvio, Zilli Alessandra

机构信息

Department of Gastroenterology and Endoscopy, IRCCS Ospedale San Raffaele and Vita-Salute San Raffaele University, Milan, Italy.

出版信息

J Crohns Colitis. 2025 May 8;19(5). doi: 10.1093/ecco-jcc/jjae174.

Abstract

A 62-year-old woman presented with multiple ileal and colonic stenoses, initially suspected to be Crohn's disease. Despite unremarkable endoscopic biopsies, surgery was performed due to clinical deterioration, and histological analysis confirmed the presence of metastatic breast cancer. This case highlights the importance of considering metastatic disease in the differential diagnosis of gastrointestinal (GI) strictures, particularly when inflammatory bowel disease markers are inconclusive or marginal. Clinicians should be aware of the potential for breast cancer to metastasize to the GI tract, which may present with symptoms mimicking primary GI diseases.

摘要

一名62岁女性出现多处回肠和结肠狭窄,最初怀疑是克罗恩病。尽管内镜活检结果无异常,但由于临床病情恶化仍进行了手术,组织学分析证实存在转移性乳腺癌。该病例强调了在胃肠道(GI)狭窄的鉴别诊断中考虑转移性疾病的重要性,特别是当炎症性肠病标志物不确定或不明显时。临床医生应意识到乳腺癌转移至胃肠道的可能性,其可能表现出类似原发性胃肠道疾病的症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d177/12087567/966c836baf22/jjae174_fig7.jpg

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