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克罗恩病合并多发狭窄和内瘘,临床表现酷似小肠子宫内膜异位症。

Crohn's disease complicated by multiple stenoses and internal fistulas clinically mimicking small bowel endometriosis.

作者信息

Teke Zafer, Aytekin Faruk Onder, Atalay Ali Ozgur, Demirkan Nese Calli

机构信息

Department of General Surgery, Pamukkale University, School of Medicine, Kuspinar Mah. Emek Cad. Oyku Sitesi, Denizli, Turkey.

出版信息

World J Gastroenterol. 2008 Jan 7;14(1):146-51. doi: 10.3748/wjg.14.146.

Abstract

We report a 31-year-old woman with Crohn's disease complicated by multiple stenoses and internal fistulas clinically misdiagnosed as small bowel endometriosis, due to the patient's perimenstrual symptoms of mechanical subileus for 3 years; at first monthly, but later continuous, and gradually increasing in severity. We performed an exploratory laparotomy for small bowel obstruction, and found multiple ileal strictures and internal enteric fistulas. Because intraoperative findings were thought to indicate Crohn's disease, a right hemicolectomy and partial distal ileum resection were performed for obstructive Crohn's ileitis. Histopathology of the resected specimen revealed Crohn's disease without endometrial tissue. The patient made an uneventful recovery from this procedure and was discharged home 10 d post-operatively. The differential diagnosis of Crohn's disease with intestinal endometriosis may be difficult pre-operatively. The two entities share many overlapping clinical, radiological and pathological features. Nevertheless, when it is difficult to identify the cause of intestinal obstruction in a woman of child-bearing age with cyclical symptoms suggestive of small bowel endometriosis, Crohn's disease should be included in the differential diagnosis.

摘要

我们报告一名31岁患有克罗恩病的女性,该病合并多处狭窄和内瘘,临床上被误诊为小肠子宫内膜异位症,原因是患者出现机械性低位肠梗阻的经前症状长达3年;起初为每月发作一次,但后来持续发作,且严重程度逐渐增加。我们针对小肠梗阻进行了剖腹探查术,发现多处回肠狭窄和肠内瘘。由于术中发现被认为提示克罗恩病,遂对梗阻性克罗恩性回肠炎行右半结肠切除术及部分远端回肠切除术。切除标本的组织病理学检查显示为克罗恩病,未见子宫内膜组织。患者术后恢复顺利,术后10天出院。术前鉴别克罗恩病与肠道子宫内膜异位症可能存在困难。这两种疾病在临床、放射学和病理学特征上有许多重叠之处。然而,当难以确定具有提示小肠子宫内膜异位症周期性症状的育龄期女性肠梗阻的病因时,鉴别诊断应包括克罗恩病。

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