Ko Jein, Kim Jongwook, Ki Kanghyun, Moon Soyoon, Jeon Hyunjin, Park Jin Hyeok, Golla Murali, Chun Chan Joo, Kim Jong Sik, Lee Anna, Kim Hyoungsoo, Park Sarah S, Shim Tae Soup, Park So-Jung
Department of Chemistry and Nanoscience, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-gu, Seoul 03760, Republic of Korea.
Department of Mechanical Engineering, Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea.
Nano Lett. 2025 Jan 8;25(1):419-425. doi: 10.1021/acs.nanolett.4c05189. Epub 2024 Dec 16.
The shape-dependent aero- and hydro-dynamics found in nature have been adopted in a wide range of areas spanning from daily transportation to forefront biomedical research. Here, we report DNA-linked nanoparticle films exhibiting shape-dependent magnetic locomotion, controlled by DNA sequences. Fabricated through a DNA-directed layer-by-layer assembly of iron oxide and gold nanoparticles, the multifunctional films exhibit rotational and translational motions under magnetic fields, along with reversible shape morphing via DNA strand exchange reactions. Notably, the shape of the film significantly influences its magnetic responsiveness, attributable to shape-dependent drag forces acting on mesoscopic films. The distinctive shape dependence combined with the shape-changing capability offers an approach to regulate magnetic locomotion within a constant magnetic field, as demonstrated here through the go and stop motion of nanoparticle films without altering the magnetic field.
自然界中发现的形状依赖的空气动力学和流体动力学已被广泛应用于从日常交通到前沿生物医学研究等众多领域。在此，我们报告了由DNA序列控制的、呈现形状依赖磁驱动的DNA连接纳米颗粒薄膜。通过氧化铁和金纳米颗粒的DNA定向逐层组装制备而成，这些多功能薄膜在磁场下表现出旋转和平移运动，同时通过DNA链交换反应实现可逆的形状变形。值得注意的是，薄膜的形状显著影响其磁响应性，这归因于作用于介观薄膜的形状依赖阻力。独特的形状依赖性与形状改变能力相结合，提供了一种在恒定磁场内调节磁驱动的方法，如此处通过纳米颗粒薄膜的前进和停止运动所示，而无需改变磁场。
