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暂时性棘层松解性皮病(格罗弗病)的免疫荧光研究

Immunofluorescence studies in transient acantholytic dermatosis (Grover's disease).

作者信息

Bystryn J C

出版信息

Am J Dermatopathol. 1979 Winter;1(4):325-7. doi: 10.1097/00000372-197900140-00006.

DOI:10.1097/00000372-197900140-00006
PMID:396810
Abstract

Abnormalities were found by immunofluorescence in five of 11 (45%) patients with transient acantholytic dermatosis. There was no consistent pattern to the abnormalities; for example, they were circulating antibodies to intercellular and basal cell antigens in a third. Deposits of Ig and/or C3 were present in lesions of three patients and C3 was present in the intercellular substance in the lesions of a fourth patient. These findings suggest that different immune mechanisms may be involved in the pathogenesis of transient acantholytic dermatosis.

摘要

在11例暂时性棘层松解性皮病患者中,有5例(45%)通过免疫荧光检查发现异常。这些异常并无一致的模式;例如,三分之一的患者体内存在针对细胞间和基底细胞抗原的循环抗体。3例患者的皮损中有Ig和/或C3沉积,第4例患者皮损的细胞间质中有C3存在。这些发现提示,不同的免疫机制可能参与了暂时性棘层松解性皮病的发病过程。

相似文献

1
Immunofluorescence studies in transient acantholytic dermatosis (Grover's disease).暂时性棘层松解性皮病(格罗弗病)的免疫荧光研究
Am J Dermatopathol. 1979 Winter;1(4):325-7. doi: 10.1097/00000372-197900140-00006.
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Persistent acantholytic dermatosis. A variant of transient acantholytic dermatosis (Grover disease).持久性棘层松解性皮病。一种暂时性棘层松解性皮病(格罗弗病)的变体。
Arch Dermatol. 1976 Oct;112(10):1429-31. doi: 10.1001/archderm.112.10.1429.
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Is Grover's disease an autoimmune dermatosis?格罗弗病是否为一种自身免疫性皮肤病?
Exp Dermatol. 2013 Dec;22(12):781-4. doi: 10.1111/exd.12266.
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[Grover's acantholytic dermatosis (transient acantholytic dermatosis) (author's transl)].[格罗弗棘层松解性皮肤病(暂时性棘层松解性皮肤病)(作者译)]
Ann Dermatol Venereol. 1979 Dec;106(12):995-9.
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Transient acantholytic dermatosis (Grover's disease) in a renal transplant patient.一名肾移植患者的暂时性棘层松解性皮肤病(格罗弗病)
J Dermatol. 2006 Mar;33(3):178-81. doi: 10.1111/j.1346-8138.2006.00041.x.
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Bullous transient acantholytic dermatosis.
Arch Dermatol. 1976 Oct;112(10):1440-1.
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[Experimental acantholysis by the complement fixing intercellular antibodies (author's transl)].补体固定性细胞间抗体所致的实验性棘层松解(作者译)
Nihon Hifuka Gakkai Zasshi. 1981 Jul;91(8):815-21.
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Grover's disease (transient acantholytic dermatosis): relationship of acantholysis to acrosyringia.格罗弗病(暂时性棘层松解性皮病):棘层松解与顶泌汗腺导管的关系
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[Transient acantholytic dermatosis (Grover's disease)].[暂时性棘层松解性皮病(格罗弗病)]
Ned Tijdschr Geneeskd. 1982 Mar 6;126(10):418-20.
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Monolateral Grover's Disease with Blaschkoid Distribution.具有布拉斯科线样分布的单侧格罗弗病
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