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Mitochondrial dysfunction has a central role in diabetic kidney disease.

作者信息

Li Shen, Susztak Katalin

机构信息

Department of Medicine, Renal Electrolyte and Hypertension Division, University of Pennsylvania, Philadelphia, PA, USA.

Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

出版信息

Nat Rev Nephrol. 2025 Feb;21(2):77-78. doi: 10.1038/s41581-024-00919-w.

DOI:10.1038/s41581-024-00919-w
PMID:39681602
Abstract
摘要

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J Clin Invest. 2024 Dec 4;135(2):e171164. doi: 10.1172/JCI171164.
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Glycolytic lactate in diabetic kidney disease.糖尿病肾病中的糖酵解乳酸。
JCI Insight. 2024 Jun 10;9(11):e168825. doi: 10.1172/jci.insight.168825.
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Transcriptomic, epigenomic, and spatial metabolomic cell profiling redefines regional human kidney anatomy.转录组学、表观基因组学和空间代谢组学细胞分析重新定义了区域人类肾脏解剖结构。
益气养阴通络方通过AGE-RAGE信号轴减轻糖尿病肾病
Diabetes Metab Syndr Obes. 2025 Jun 28;18:2041-2055. doi: 10.2147/DMSO.S523784. eCollection 2025.
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Editorial: Diabetic kidney disease: routes to drug development, pharmacology and underlying molecular mechanisms, volume II.社论:糖尿病肾病:药物研发途径、药理学及潜在分子机制,第二卷
Front Pharmacol. 2025 Apr 25;16:1609100. doi: 10.3389/fphar.2025.1609100. eCollection 2025.
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A novel fullerene-lysine derivative with noticeable ROS scavenging capabilities for improving type 2 diabetes mellitus.一种具有显著活性氧清除能力的新型富勒烯-赖氨酸衍生物,用于改善2型糖尿病。
Nanoscale Adv. 2025 Apr 26. doi: 10.1039/d4na01081g.
Cell Metab. 2024 May 7;36(5):1105-1125.e10. doi: 10.1016/j.cmet.2024.02.015. Epub 2024 Mar 20.
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Nat Commun. 2024 Mar 4;15(1):1965. doi: 10.1038/s41467-024-46366-w.
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