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营养保健品:医疗保健领域一个前景广阔但尚未规范的前沿领域。

Nutraceuticals: a promising, yet unregulated Frontier in Healthcare.

作者信息

Takefuji Yoshiyasu

机构信息

Faculty of Data Science, Musashino University, Tokyo, Japan.

出版信息

Eur J Clin Nutr. 2025 May;79(5):413-418. doi: 10.1038/s41430-024-01557-y. Epub 2024 Dec 16.

DOI:10.1038/s41430-024-01557-y
PMID:39681616
Abstract

Nutraceuticals, with their potential health benefits, are increasingly being used to manage a variety of health conditions. The global market for nutraceuticals, valued at USD 540 billion in 2022, is projected to reach USD 1025 billion by 2030. This paper delves into the beneficial impacts of emerging nutraceuticals on a spectrum of medical disorders, drawing from credible sources from the National Library of Medicine. We have scrutinized studies on the application of nutraceuticals in treating conditions like sleep disorders, migraines, oxidative stress, mental health issues, pain disorders, obesity, gastrointestinal disorders, and even COVID-19. Our analysis indicates that nutraceuticals hold promise for addressing various health issues. However, this paper also sheds light on the health risks associated with nutraceuticals. Despite their widespread use, the safety and efficacy of nutraceuticals are still uncertain due to the lack of stringent regulations, unlike pharmaceutical drugs. This raises concerns about potential health risks and misleading claims. Research indicates that some supplements can cause adverse effects and interact with medications. Therefore, to ensure safe usage, it is imperative to implement stricter regulations, enhance reporting systems, and boost consumer awareness.

摘要

营养保健品因其潜在的健康益处,正越来越多地被用于管理各种健康状况。2022年全球营养保健品市场价值5400亿美元,预计到2030年将达到10250亿美元。本文借鉴美国国立医学图书馆的可靠资料,深入探讨新兴营养保健品对一系列医学病症的有益影响。我们仔细研究了营养保健品在治疗睡眠障碍、偏头痛、氧化应激、心理健康问题、疼痛障碍、肥胖症、胃肠道疾病甚至新冠肺炎等病症方面的应用研究。我们的分析表明,营养保健品在解决各种健康问题方面具有前景。然而,本文也揭示了与营养保健品相关的健康风险。尽管营养保健品被广泛使用,但与药品不同,由于缺乏严格监管,其安全性和有效性仍不确定。这引发了对潜在健康风险和误导性宣称的担忧。研究表明,一些补充剂会产生不良反应并与药物相互作用。因此,为确保安全使用,必须实施更严格的监管、加强报告系统并提高消费者意识。

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Compr Rev Food Sci Food Saf. 2025 Sep;24(5):e70279. doi: 10.1111/1541-4337.70279.

本文引用的文献

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Nutraceuticals in Psychiatric Disorders: A Systematic Review.精神障碍中的营养保健品:系统评价。
Int J Mol Sci. 2024 Apr 28;25(9):4824. doi: 10.3390/ijms25094824.
2
Antiviral, anti-inflammatory and antioxidant effects of curcumin and curcuminoids in SH-SY5Y cells infected by SARS-CoV-2.姜黄素和姜黄素类化合物对 SARS-CoV-2 感染的 SH-SY5Y 细胞的抗病毒、抗炎和抗氧化作用。
Sci Rep. 2024 May 10;14(1):10696. doi: 10.1038/s41598-024-61662-7.
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Sports-Related Gastrointestinal Disorders: From the Microbiota to the Possible Role of Nutraceuticals, a Narrative Analysis.
与运动相关的胃肠道疾病:从微生物群到营养保健品的潜在作用,一项叙述性分析
Microorganisms. 2024 Apr 16;12(4):804. doi: 10.3390/microorganisms12040804.
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Neuroinflammation and Schizophrenia: New Therapeutic Strategies through Psychobiotics, Nanotechnology, and Artificial Intelligence (AI).神经炎症与精神分裂症:通过心理益生菌、纳米技术和人工智能(AI)的新治疗策略
J Pers Med. 2024 Apr 6;14(4):391. doi: 10.3390/jpm14040391.
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The role of the GABAergic system on insomnia.γ-氨基丁酸能系统在失眠中的作用。
Tzu Chi Med J. 2024 Mar 26;36(2):103-109. doi: 10.4103/tcmj.tcmj_243_23. eCollection 2024 Apr-Jun.
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The Role of Gut Microbiota, Nutrition, and Physical Activity in Depression and Obesity-Interdependent Mechanisms/Co-Occurrence.肠道微生物群、营养和身体活动在抑郁症和肥胖症中的作用——相互依存的机制/共同发生。
Nutrients. 2024 Apr 2;16(7):1039. doi: 10.3390/nu16071039.
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An overview of regulation for nutraceuticals and concept of personalized nutraceuticals.营养保健品的监管概述及个性化营养保健品的概念。
J Generic Med. 2023 Jun;19(2):66-74. doi: 10.1177/17411343221150875. Epub 2023 Jan 13.
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Predispose, precipitate, perpetuate, and protect: how diet and the gut influence mental health in emerging adulthood.易患、促成、延续与保护:饮食与肠道如何影响成年早期的心理健康
Front Nutr. 2024 Mar 5;11:1339269. doi: 10.3389/fnut.2024.1339269. eCollection 2024.
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Cancers (Basel). 2024 Feb 22;16(5):880. doi: 10.3390/cancers16050880.
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Benefit of Dietary Supplementation of Nutraceuticals as an Integrative Approach for Management of Migraine: Evidence From Preclinical and Clinical Studies.营养保健品的膳食补充作为偏头痛管理的综合方法的益处:来自临床前和临床研究的证据。
Curr Pain Headache Rep. 2024 May;28(5):373-381. doi: 10.1007/s11916-024-01230-w. Epub 2024 Mar 2.