Marx Pieter, Marais Henri
Faculty of Engineering, North-West University, Potchefstroom 2531, South Africa.
Diagnostics (Basel). 2024 Nov 21;14(23):2616. doi: 10.3390/diagnostics14232616.
Mechanical ventilation is a critical but resource-intensive treatment. Automated tools are common in screening diagnostics, whereas real-time, continuous trend analysis in mechanical ventilation remains rare. Current techniques for monitoring lung conditions are often invasive, lack accuracy, and fail to isolate respiratory resistance-making them impractical for continuous monitoring and diagnosis. To address this challenge, we propose an automated, non-invasive condition monitoring method to support pulmonologists.
Our method leverages ventilation waveform time-series data in controlled modes to monitor lung conditions automatically and non-invasively on a breath-by-breath basis while accurately isolating respiratory resistance.
Using statistical classification and regression models, the approach achieves 99.1% accuracy for ventilation mode classification, 97.5% accuracy for feature extraction, and 99.0% for predicting mechanical lung parameters. The models are both computationally efficient (720 K predictions per second per core) and lightweight (24.5 MB).
By storing breath-by-breath predictions, pulmonologists can access a high-resolution trend of lung conditions, gaining clear insights into sudden changes without speculation and streamlining diagnosis and decision-making. The deployment of this solution could expand domain knowledge, enhance the understanding of patient conditions, and enable real-time dashboards for parallel monitoring, helping to prioritize patients and optimize resource use, which is especially valuable during pandemics.
机械通气是一种关键但资源密集型的治疗方法。自动化工具在筛查诊断中很常见,而机械通气中的实时、连续趋势分析仍然很少见。当前监测肺部状况的技术通常具有侵入性,缺乏准确性,并且无法分离呼吸阻力,这使得它们对于连续监测和诊断不切实际。为应对这一挑战,我们提出了一种自动化、非侵入性的状况监测方法,以支持肺科医生。
我们的方法利用受控模式下的通气波形时间序列数据,在逐次呼吸的基础上自动、非侵入性地监测肺部状况,同时准确分离呼吸阻力。
使用统计分类和回归模型,该方法在通气模式分类方面的准确率达到99.1%,特征提取方面的准确率达到97.5%,预测肺部机械参数方面的准确率达到99.0%。这些模型在计算上都很高效(每个核心每秒720K次预测)且轻量级(24.5MB)。
通过存储逐次呼吸的预测结果,肺科医生可以获取肺部状况的高分辨率趋势,无需猜测就能清晰洞察突然变化,简化诊断和决策过程。该解决方案的部署可以扩展领域知识,增强对患者状况的理解,并启用实时仪表板进行并行监测,有助于确定患者优先级并优化资源利用,这在大流行期间尤其有价值。