Villamil Ruby-Alejandra, Romero Laura-Natalia, Ruiz Juan-Pablo, Patiño Diana-Cristina, Gutiérrez Luis-Felipe, Cortés Lilia-Yadira
Departamento de Nutrición y Bioquímica, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.
Departamento de Microbiología, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.
Foods. 2024 Dec 9;13(23):3973. doi: 10.3390/foods13233973.
Sacha Inchi oil (SIO) and hybrid palm oil (HPO) are potential sources of unsaturated fatty acids to improve the lipid profile of dairy products. This study evaluated, for the first time, the effects of the daily consumption of yogurts with enhanced fatty acid profiles on plasma lipids related to cardiovascular disease (CVD) risk factors. A pilot, randomized, double-blind, parallel-controlled trial was conducted with 47 participants assigned to three groups: SIO-enriched yogurt (Group A), HPO-enriched yogurt (Group B), and plain yogurt (Group C). Fasting blood samples were collected at baseline and after 1, 2, and 3 months to measure plasma lipids (TC, LDL-C, HDL-C, and TAG), ApoA1, and ApoB. While no significant changes were observed in the overall lipid profiles, notable within-group effects were identified. The total cholesterol (TC) dropped by 2.8%, 1.3%, and 3.3%, and LDL-C by 1.6%, 2.5%, and 2% in Groups A, B, and C, respectively. Additionally, the intake of monounsaturated fatty acids (MUFA), polyunsaturated fatty acids (PUFA), and vitamin E significantly increased in Groups A and B. These results suggest that SIO and HPO can be used as milk fat substitutes to enhance the nutritional profile of yogurts without affecting CVD biomarkers in healthy individuals.
沙棘籽油(SIO)和杂交棕榈油(HPO)是不饱和脂肪酸的潜在来源,可改善乳制品的脂质状况。本研究首次评估了每日食用脂肪酸谱增强的酸奶对与心血管疾病(CVD)风险因素相关的血浆脂质的影响。进行了一项试点、随机、双盲、平行对照试验,47名参与者被分为三组:富含SIO的酸奶组(A组)、富含HPO的酸奶组(B组)和普通酸奶组(C组)。在基线以及1、2和3个月后采集空腹血样,以测量血浆脂质(总胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇和甘油三酯)、载脂蛋白A1和载脂蛋白B。虽然总体脂质状况未观察到显著变化,但在组内发现了显著影响。A组、B组和C组的总胆固醇(TC)分别下降了2.8%、1.3%和3.3%,低密度脂蛋白胆固醇分别下降了1.6%、2.5%和2%。此外,A组和B组的单不饱和脂肪酸(MUFA)、多不饱和脂肪酸(PUFA)和维生素E的摄入量显著增加。这些结果表明,SIO和HPO可用作乳脂肪替代品,以增强酸奶的营养成分,而不影响健康个体的CVD生物标志物。