Formisano Annarita, Russo Marika Dello, Russo Paola, Siani Alfonso, Hinojosa-Nogueira Daniel, Navajas-Porras Beatriz, Toledano-Marín Ángela, Pastoriza Silvia, Blasco Telmo, Lerma-Aguilera Alberto, Francino María Pilar, Planes Francisco Javier, González-Vigil Verónica, Rufián-Henares José Ángel, Lauria Fabio
Institute of Food Science, National Research Council of Italy, 83100 Avellino, Italy.
Department of Precision Medicine, University of Campania "L. Vanvitelli", 80138 Naples, Italy.
Nutrients. 2024 Nov 26;16(23):4064. doi: 10.3390/nu16234064.
: Diet significantly influences gut microbiota (GM), with variations in GM responses linked to the type and quantity of food consumed. These variations underscore the need for personalized nutrition. The Stance4Health (S4H) project developed the S4H Food Frequency Questionnaire (S4H-FFQ) and the i-Diet S4H app to assess dietary intake of foods affecting GM. This study aimed to validate the S4H-FFQ against the validated I.Family-FFQ and the i-Diet S4H app; The S4H-FFQ, with 200 food items across 14 food groups, evaluates dietary intake over the past month. Qualitative validation compared food group consumption frequencies from the S4H-FFQ and the I.Family-FFQ, while quantitative validation assessed nutrient and energy intake using the i-Diet S4H app. The S4H-GM score, a measure of GM-relevant food consumption, was evaluated through the S4H-FFQ and i-Diet S4H app; : Pearson correlations between the S4H-FFQ and the I.Family-FFQ ranged from 0.3 to 0.7 and were statistically significant across all the food groups. Quantitative validation showed lower but consistent correlations, comparable with other studies, confirming the S4H-FFQ's ability to estimate food intake. A positive correlation was also found between the S4H-GM scores from the S4H-FFQ and the i-Diet S4H app ( < 0.001); : The S4H-FFQ is a reliable tool for assessing dietary patterns that influence GM. Its application in nutritional studies can enhance personalized nutrition and support future research aimed at optimizing GM and improving health outcomes.
饮食对肠道微生物群（GM）有显著影响，GM反应的变化与所摄入食物的类型和数量有关。这些变化凸显了个性化营养的必要性。Stance4Health（S4H）项目开发了S4H食物频率问卷（S4H-FFQ）和i-Diet S4H应用程序，以评估影响GM的食物的饮食摄入量。本研究旨在对照经过验证的I.Family-FFQ和i-Diet S4H应用程序对S4H-FFQ进行验证；S4H-FFQ涵盖14个食物组中的200种食物，评估过去一个月的饮食摄入量。定性验证比较了S4H-FFQ和I.Family-FFQ中食物组的消费频率，而定性验证则使用i-Diet S4H应用程序评估营养素和能量摄入量。通过S4H-FFQ和i-Diet S4H应用程序评估了S4H-GM评分，这是一种与GM相关食物消费的衡量指标；S4H-FFQ与I.Family-FFQ之间的Pearson相关性在0.3至0.7之间，并且在所有食物组中均具有统计学意义。定量验证显示相关性较低但一致，与其他研究相当，证实了S4H-FFQ估计食物摄入量的能力。在S4H-FFQ和i-Diet S4H应用程序的S4H-GM评分之间也发现了正相关（<0.001）；S4H-FFQ是评估影响GM的饮食模式的可靠工具。它在营养研究中的应用可以增强个性化营养，并支持未来旨在优化GM和改善健康结果的研究。
