Kaneko Kiyoko, Tsuruga Keito, Takayanagi Fukue, Fukuuchi Tomoko, Yamaoka Noriko, Seki Reiko, Fujimori Shin
Biomolecular Logic Research Laboratory, Kita-ku, Tokyo 114-0023, Japan.
Faculty of Pharmaceutical Sciences, Teikyo University, Itabashi-ku, Tokyo 173-8605, Japan.
Nutrients. 2024 Nov 27;16(23):4066. doi: 10.3390/nu16234066.
A low purine diet has been recommended for patients with gout and hyperuricemia, but there are concerns about excessive carbohydrates and a lack of protein. A well-balanced diet in accordance with general dietary guidelines is widely recommended. The Mediterranean diet and the DASH (Dietary Approaches to Stop Hypertension) diet are also recommended for gout and hyperuricemia patients. However, there is little information on the purine levels in these diets. The aim of this study is to determine the daily amount of purine in well-balanced diets that follows the dietary guidelines, including the Mediterranean diet and the DASH diet. : We measured the purine content in various foodstuffs. Using these values, we calculated the amount of purine in generally recommended well-balanced diets-the Japanese diet, American My Plate Plan, the Mediterranean diet, and the DASH diet. To calculate the amount of purine, recipes tailored to the characteristics of each diet were created. : The amount of purine in the Japanese diet, in the American My Plate Plan, in the Mediterranean diet, and in the DASH diet were 308.5-366.1, 308.7-335.0, 346.6-394.1, 325.9-493.9 mg/day, respectively. These values were close to the 400 mg/day recommended in the Japanese Guideline for the management of Hyperuricemia and Gout. : A well-balanced diet following the recommendation in the dietary guidelines is considered to provide adequate purines. Because a high purine diet can lead to the recurrence of gout, advising to eat a balanced diet is useful on lifestyle guidance for the patients with gout and hyperuricemia.
痛风和高尿酸血症患者建议采用低嘌呤饮食，但人们担心碳水化合物过量和蛋白质缺乏。广泛推荐符合一般饮食指南的均衡饮食。地中海饮食和DASH（终止高血压膳食方法）饮食也适用于痛风和高尿酸血症患者。然而，关于这些饮食中嘌呤水平的信息很少。本研究的目的是确定遵循饮食指南的均衡饮食（包括地中海饮食和DASH饮食）中每日嘌呤的含量。我们测量了各种食品中的嘌呤含量。利用这些数值，我们计算了一般推荐的均衡饮食（日本饮食、美国我的餐盘计划、地中海饮食和DASH饮食）中的嘌呤含量。为了计算嘌呤含量，我们根据每种饮食的特点制定了食谱。日本饮食、美国我的餐盘计划、地中海饮食和DASH饮食中的嘌呤含量分别为308.5 - 366.1、308.7 - 335.0、346.6 - 394.1、325.9 - 493.9毫克/天。这些数值接近日本高尿酸血症和痛风管理指南中推荐的400毫克/天。遵循饮食指南建议的均衡饮食被认为能提供足够的嘌呤。由于高嘌呤饮食会导致痛风复发，建议痛风和高尿酸血症患者均衡饮食对生活方式指导很有用。
