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兰花的抗血小板、抗凝和纤溶活性:综述

Antiplatelet, Anticoagulant, and Fibrinolytic Activity of Orchids: A Review.

作者信息

Fernández-Rojas Berenice, López-Pérez Abimael, Lagunez-Rivera Luicita, Solano Rodolfo, Bernal-Martínez Anel Karina, Majluf-Cruz Abraham, Hernández-Juárez Jesús

机构信息

Laboratorio de Nutracéuticos y Productos Naturales, Centro de Estudios en Ciencias de la Salud y la Enfermedad, Facultad de Odontología, Universidad Autónoma Benito Juárez de Oaxaca, Oaxaca 68120, Mexico.

Centro Interdisciplinario de Investigación para el Desarrollo Integral Regional Unidad Oaxaca, Instituto Politécnico Nacional, Oaxaca 71233, Mexico.

出版信息

Molecules. 2024 Dec 3;29(23):5706. doi: 10.3390/molecules29235706.

DOI:10.3390/molecules29235706
PMID:39683865
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11643684/
Abstract

Thrombosis is the occlusion of a blood vessel and is responsible for the highest number of deaths worldwide. Its treatment comprises the use of anticoagulants, antiplatelets, and thrombolytics. Although many antithrombotic drugs are currently available, none is completely effective and safe. Plants are a valuable source of compounds with antithrombotic properties. Some orchid species have been used in traditional medicine for their antithrombotic properties. This review informs about the contribution of orchids in this field and the studies that have validated their properties.

摘要

血栓形成是血管的阻塞,是全球范围内导致死亡人数最多的原因。其治疗方法包括使用抗凝剂、抗血小板药物和溶栓剂。尽管目前有许多抗血栓药物,但没有一种是完全有效和安全的。植物是具有抗血栓特性化合物的宝贵来源。一些兰花品种因其抗血栓特性而被用于传统医学。这篇综述介绍了兰花在该领域的贡献以及验证其特性的研究。

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J Thromb Thrombolysis. 2024 Dec;57(8):1297-1307. doi: 10.1007/s11239-024-03023-9. Epub 2024 Jul 29.
3
Medicinal Orchids of Mexico: A Review.墨西哥的药用兰花:综述
Pharmaceuticals (Basel). 2024 Jul 8;17(7):907. doi: 10.3390/ph17070907.
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Factor XI inhibition in cardiovascular disease.XI 因子抑制在心血管疾病中的作用。
Pol Arch Intern Med. 2024 Aug 8;134(7-8). doi: 10.20452/pamw.16799. Epub 2024 Jul 9.
5
The convergent model of coagulation.凝血的会聚模型。
J Thromb Haemost. 2024 Aug;22(8):2140-2146. doi: 10.1016/j.jtha.2024.05.014. Epub 2024 May 28.
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Development of new anticoagulant in 2023: Prime time for anti-factor XI and XIa inhibitors.2023 年新型抗凝药物的研发:抗因子 XI 和因子 XIa 抑制剂的黄金时代。
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