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（林德利）林德利 ex G. 唐的植物化学、抗氧化、抗炎和溶栓特性

Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of (Lindl.) Lindl. ex G. Don.

作者信息

Rahman Minhajur, Surag Abu Taleb, Begum Roxy, Hossain Tusher Md Shakhuat, Huda Mohammed Kamrul

机构信息

Department of Botany, University of Chittagong, Chittagong, Bangladesh.

Ecology and Phytochemistry Lab, Department of Botany, University of Chittagong, Chittagong, Bangladesh.

出版信息

Scientifica (Cairo). 2022 May 26;2022:5660527. doi: 10.1155/2022/5660527. eCollection 2022.

DOI:10.1155/2022/5660527
PMID:35664371
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9162869/
Abstract

For the first time, (family: Orchidaceae) has been investigated for its phytochemical, antioxidant, anti-inflammatory, and thrombolytic properties. All phytochemicals studied were identified in varying degrees during qualitative screening. In quantitative screening, a maximum of 106.02 ± 0.08 mg/g alkaloids (root), 179.67 ± 8.83 mg/g phenols (stem), 17.34 ± 0.88 mg/g flavonoids (stem), 73.67 ± 1.76 mg/g tannins (stem), and 180.04 ± 0.02 g/mL proteins (root) were detected. Antioxidant, anti-inflammatory, and thrombolytic properties were investigated using a free-radical scavenging assay, heat-induced albumin denaturation assay, and blood clotting inhibition assay. The root extracts had the most effective antioxidant (IC = 67.98 g/mL) and anti-inflammatory (IC = 60.86 g/mL) properties, whereas the stem extracts had the most effective thrombolytic property (IC = 163.8 g/mL). The bioactivities studied also had a significant positive relationship ( = 0.9;   <  0.05) with the amount of phenolics and tannins.

摘要

首次对（兰科）进行了植物化学、抗氧化、抗炎和溶栓特性的研究。在定性筛选过程中，所有研究的植物化学物质都得到了不同程度的鉴定。在定量筛选中，检测到的生物碱含量最高为106.02±0.08毫克/克（根）、酚类为179.67±8.83毫克/克（茎）、黄酮类为17.34±0.88毫克/克（茎）、单宁为73.67±1.76毫克/克（茎）、蛋白质为180.04±0.02克/毫升（根）。使用自由基清除试验、热诱导白蛋白变性试验和凝血抑制试验研究了抗氧化、抗炎和溶栓特性。根提取物具有最有效的抗氧化（IC = 67.98克/毫升）和抗炎（IC = 60.86克/毫升）特性，而茎提取物具有最有效的溶栓特性（IC = 163.8克/毫升）。所研究的生物活性与酚类和单宁的含量也具有显著的正相关关系（ = 0.9； ＜ 0.05）。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b72/9162869/e91bcd81062d/SCIENTIFICA2022-5660527.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b72/9162869/613448a3fd51/SCIENTIFICA2022-5660527.001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b72/9162869/554dfbb249d3/SCIENTIFICA2022-5660527.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b72/9162869/aeace81120cb/SCIENTIFICA2022-5660527.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b72/9162869/9a85cba20df0/SCIENTIFICA2022-5660527.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b72/9162869/22cac77bd23d/SCIENTIFICA2022-5660527.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b72/9162869/e91bcd81062d/SCIENTIFICA2022-5660527.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b72/9162869/613448a3fd51/SCIENTIFICA2022-5660527.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b72/9162869/df54824a7cdc/SCIENTIFICA2022-5660527.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b72/9162869/554dfbb249d3/SCIENTIFICA2022-5660527.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b72/9162869/aeace81120cb/SCIENTIFICA2022-5660527.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b72/9162869/9a85cba20df0/SCIENTIFICA2022-5660527.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b72/9162869/22cac77bd23d/SCIENTIFICA2022-5660527.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b72/9162869/e91bcd81062d/SCIENTIFICA2022-5660527.007.jpg

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