Puglisi Roberta, Testa Caterina, Scuderi Sara, Greco Valentina, Trusso Sfrazzetto Giuseppe, Petroselli Manuel, Pappalardo Andrea
Department of Chemical Science, University of Catania, 95125 Catania, Italy.
Center for Supramolecular Chemistry and Catalysis and Department of Chemistry, College of Science, Shanghai University, Shanghai 200444, China.
Molecules. 2024 Dec 8;29(23):5796. doi: 10.3390/molecules29235796.
Amines are produced through various industrial and biological processes, contributing significantly to atmospheric pollution, particularly in the troposphere. Moreover, amine-related pollution raises global concerns due to its detrimental effects on human health, environmental quality, and the preservation of animal species. Low-molecular-weight volatile amines, categorized as volatile organic compounds (VOCs), are present in the atmosphere, and they represent the main cause of air pollution. Biogenic amines, resulting from the natural decarboxylation of amino acids, are released into the environment from both natural and industrial sources. Several methods have been developed so far to detect amines in the environment. In this study, we present a novel fluorescent receptor based on a Zn-Salen complex, functionalized with pyrenyl moieties and a chiral diamine bridge, to enhance its affinity for a broad range of amines. Fluorescence titrations and density functional theory (DFT) calculations reveal and explain the high binding affinity of this receptor toward selected amines, demonstrating its potential as an effective tool for amine detection.
胺类物质通过各种工业和生物过程产生，对大气污染有显著影响，尤其是在对流层。此外，与胺相关的污染因其对人类健康、环境质量和动物物种保护的有害影响而引起全球关注。低分子量挥发性胺类物质属于挥发性有机化合物（VOCs），存在于大气中，是空气污染的主要原因。生物胺由氨基酸的自然脱羧作用产生，从自然源和工业源释放到环境中。到目前为止，已经开发了几种方法来检测环境中的胺类物质。在本研究中，我们提出了一种基于锌-萨伦配合物的新型荧光受体，其用芘基部分和手性二胺桥进行功能化，以增强其对多种胺类物质的亲和力。荧光滴定和密度泛函理论（DFT）计算揭示并解释了该受体对选定胺类物质的高结合亲和力，证明了其作为胺类检测有效工具的潜力。
