Zou Zhao-Jun, Song Hai-Xin, Wang Ting, Ma Hai-Yun, Cao Li-Ping, Wu Tao
Nursing Department, Shaw Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Department of Rehabilitation Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Medicine (Baltimore). 2024 Dec 13;103(50):e40847. doi: 10.1097/MD.0000000000040847.
Intermittent pneumatic compression (IPC) and neuromuscular electrical stimulation can improve deep vein hemodynamics in the lower limbs. We developed a new, small and convenient, and easy to wear common peroneal nerve electrical stimulator (CPNES) and to investigate the effectiveness and safety of CPNES intervention on deep venous hemodynamics.
Thirty healthy volunteers were recruited and randomly divided into group A and B. In group A, the hemodynamics of the left superficial femoral artery and the superficial femoral vein were measured after IPC compression, and then the CPNES was activated and the hemodynamics was measured again. In group B, the order of intervention was reversed.
In group A, the peak velocity, time average blood flow velocity (TAMV), and flow velocity of femoral vein after IPC and CPNES intervention were higher than these of the baseline (P < .05, respectively). No significant differences of these blood flow parameters were found between IPC and CPNES intervention (P > .05, respectively). In group B, these blood flow parameters of femoral vein after IPC and CPNES intervention were higher than these of the baseline (P < .05, respectively). No significant difference of these blood flow parameters (P > .05, respectively) were noted between IPC and CPNES intervention as well. No differential change of these flow velocity of femoral artery after IPC and CPNES intervention in group A or group B. The hemodynamics of superficial femoral arteries and veins after intervention in group A and B were similar (P > .05, respectively).
The effectiveness of CPNES intervention on the hemodynamics of the lower extremity is similar with that of IPC, increasing blood flow and may prevent venous thrombosis without adverse reaction.
间歇性气动压迫（IPC）和神经肌肉电刺激可改善下肢深静脉血流动力学。我们研发了一种新型、小巧便捷且易于穿戴的腓总神经电刺激器（CPNES），并探讨CPNES干预对深静脉血流动力学的有效性和安全性。
招募30名健康志愿者，随机分为A组和B组。A组在IPC压迫后测量左股浅动脉和股浅静脉的血流动力学，然后激活CPNES并再次测量血流动力学。B组干预顺序相反。
A组中，IPC和CPNES干预后股静脉的峰值流速、时间平均血流速度（TAMV）和流速均高于基线水平（P均<0.05）。IPC和CPNES干预之间这些血流参数无显著差异（P均>0.05）。B组中，IPC和CPNES干预后股静脉的这些血流参数也高于基线水平（P均<0.05）。IPC和CPNES干预之间这些血流参数同样无显著差异（P均>0.05）。A组或B组中，IPC和CPNES干预后股动脉流速无差异变化。A组和B组干预后股浅动脉和静脉的血流动力学相似（P均>0.05）。
CPNES干预对下肢血流动力学的有效性与IPC相似，可增加血流量并可能预防静脉血栓形成，且无不良反应。
