Chen Po-Wei, Tseng Bor-Yann, Yang Zhu-Han, Yu Chi-Hua, Lin Keng-Tse, Chen Jhen-Nong, Liu Ping-Yen
Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.
Division of Cardiology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.
iScience. 2024 Nov 4;27(12):111318. doi: 10.1016/j.isci.2024.111318. eCollection 2024 Dec 20.
Deep vein thrombosis (DVT) causes significant healthcare burdens worldwide. This study aims to establish a deep learning model for the diagnosis of DVT from the assessment of vein compressibility. Considering the complexity of ultrasound images, convolutional neural networks with UNet and residual neural network (ResNet) are established for image segmentation, from venous duplex ultrasonographic video images, obtained through standard and portable handheld ultrasound methods. To further evaluate the similarity between the predicted and ground truth images, the structural similarity index (SSIM) is employed. Our deep learning model achieves over 90% accuracy, providing an innovative tool for both images and videos. This study harnesses the power of machine learning to develop an automatic labeling tool that can diagnose DVT by analyzing ultrasonography images. To make the tool more accessible to front-line clinicians, a user-friendly application is created to quickly assess possible clinical severity and enable prompt medical intervention, reducing disease progression.
深静脉血栓形成(DVT)在全球范围内造成了巨大的医疗负担。本研究旨在通过评估静脉可压缩性建立一种用于诊断DVT的深度学习模型。考虑到超声图像的复杂性,利用带有U-Net的卷积神经网络和残差神经网络(ResNet)对通过标准和便携式手持超声方法获得的静脉双功超声视频图像进行图像分割。为了进一步评估预测图像与真实图像之间的相似度,采用了结构相似性指数(SSIM)。我们的深度学习模型准确率超过90%,为图像和视频提供了一种创新工具。本研究利用机器学习的力量开发了一种自动标注工具,该工具可以通过分析超声图像来诊断DVT。为了使一线临床医生更容易使用该工具,创建了一个用户友好的应用程序,以快速评估可能的临床严重程度并实现及时的医疗干预,从而减少疾病进展。