Pérez Centurión Vilma Teresa, Cousirat Luis, Araya Soraya, Benítez Irene, Villafañe Margarita, León Derlis, Ramírez Luisa, Snead Lyton, Rojas Agustina, Monges Pablo, Revolero Diego, Chamorro Gustavo, Cabello Águeda, Pastor Desirée
Programa Nacional de Enfermedades Inmunoprevenibles y PAI Ministerio de Salud Pública y Bienestar Social Asunción Paraguay Programa Nacional de Enfermedades Inmunoprevenibles y PAI, Ministerio de Salud Pública y Bienestar Social, Asunción, Paraguay.
Ministerio de Salud Pública y Bienestar Social Asunción Paraguay Ministerio de Salud Pública y Bienestar Social, Asunción, Paraguay.
Rev Panam Salud Publica. 2024 Dec 16;48:e96. doi: 10.26633/RPSP.2024.96. eCollection 2024.
To describe the impact of the new intervention model implemented by Paraguay across five districts of the Central Region in the last quarter of 2023, consisting of an integrated health services-based strategy to recover coverage with the tracer vaccine (pentavalent until April 2023, hexavalent thereafter) in children under 1 year of age; and the measles, mumps, and rubella (MMR) vaccine for the 1-year-old population.
Descriptive, cross-sectional study with comparative analysis before (epidemiological weeks [EW] 1 and 34 of 2023) and after (EW35 and EW52 of 2023) the intervention. Three indicators were assessed: a) coverage with all three doses of pentavalent or hexavalent vaccine and first and second doses of MMR; b) productivity, represented by third doses of pentavalent or hexavalent vaccine administered; and c) dropout rates for the pentavalent or hexavalent and MMR vaccines.
After the intervention, average weekly coverage with the third dose of pentavalent or hexavalent vaccine was 1.2%, an increase of 1.0% from the pre-intervention average. Compared to 2022, coverage with the third dose of pentavalent or hexavalent vaccine increased by 3.5% in 2023, while coverage with the first and second doses of MMR increased 32.7% and 4%, respectively. The average number of weekly third doses of pentavalent or hexavalent vaccine administered increased to 257, up from 215 prior to the intervention. The dropout rate declined from 17.9% to 9.2% for pentavalent and hexavalent vaccine and from 55.0% to 46.5% for the MMR vaccine.
Implementation of the new intervention model had a positive impact on the indicators of interest, halting the downward trend in vaccination coverage recorded in recent years.
描述巴拉圭于2023年最后一个季度在中部地区五个区实施的新干预模式的影响，该模式包括一项基于综合卫生服务的战略，旨在恢复1岁以下儿童使用追踪疫苗（2023年4月前为五价疫苗，此后为六价疫苗）以及1岁人群使用麻疹、腮腺炎和风疹（MMR）疫苗的覆盖率。
采用描述性横断面研究，并在干预前（2023年流行病学周[EW]1和34）和干预后（2023年EW35和EW52）进行对比分析。评估了三个指标：a）三剂五价或六价疫苗以及MMR疫苗第一剂和第二剂的覆盖率；b）以接种的五价或六价疫苗第三剂表示的生产率；c）五价或六价疫苗以及MMR疫苗的漏种率。
干预后，五价或六价疫苗第三剂的平均每周覆盖率为1.2%，比干预前的平均水平增加了1.0%。与2022年相比，2023年五价或六价疫苗第三剂的覆盖率提高了3.5%，而MMR疫苗第一剂和第二剂的覆盖率分别提高了32.7%和4%。每周接种的五价或六价疫苗第三剂的平均数量从干预前的215剂增加到了257剂。五价和六价疫苗的漏种率从17.9%降至9.2%，MMR疫苗的漏种率从55.0%降至46.5%。
新干预模式的实施对相关指标产生了积极影响，遏制了近年来疫苗接种覆盖率下降的趋势。
