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学校自闭症谱系社交故事试验2(ASSSIST - 2):一项实用随机对照试验,旨在研究“社交故事™”干预措施对英国小学自闭症儿童社会和情感健康的影响。

Autism Spectrum Social Stories in Schools Trial 2 (ASSSIST-2): a pragmatic randomised controlled trial of the Social Stories™ intervention to address the social and emotional health of autistic children in UK primary schools.

作者信息

Wright Barry, Blackwell Jane E, Bell Kerry J, Teige Catarina, Mandefield Laura, Wang Han-I, Welch Charlie, Scantlebury Arabella, Watson Judith, McMillan Dean, Standley Emma, Attwell Leah, Carrick Hayley, Taylor Amelia, Taylor Olivia, Hodkinson Rachel, Edwards Hannah, Pearson Hannah, Parrott Steve, Marshall David, Varley Danielle, Hargate Rebecca, Mclaren Anne, Hewitt Catherine

机构信息

Department of Health Sciences, University of York, York, UK.

Hull York Medical School, University of York, York, UK.

出版信息

Child Adolesc Ment Health. 2025 Feb;30(1):4-12. doi: 10.1111/camh.12740. Epub 2024 Dec 17.

DOI:10.1111/camh.12740
PMID:39688069
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11754701/
Abstract

BACKGROUND

Autistic children can experience mental health, social and emotional difficulties. Carol Gray's Social Stories™ are a highly personalised intervention that provide social information in a short individually tailored story.

METHODS

A multi-site pragmatic cluster randomised controlled trial to evaluate the clinical and cost-effectiveness of Social Stories™ alongside care as usual in autistic children aged 4-11 years. The primary outcome was the Social Responsiveness Scale-2 completed by teachers 6 months post-randomisation, analysed on an intention-to-treat basis.

TRIAL REGISTRATION

ISRCTN11634810.

RESULTS

Eighty-seven schools, including 249 children, were randomised (intervention 44 schools with 129 children, and usual care 43 schools with 120 children). After 6 months, a reduction of 1.61 points was found on the Social Responsiveness Scale-2 in the intervention group (95% CI -4.18 to 0.96, p = .220) and for those who attended at least six sessions a reduction of 3.37 points (CACE 95% CI -6.65 to -0.10, p = .043). Children in the intervention group met their individual socio-emotional goal more frequently than children receiving usual care alone and this was statistically significant. No statistically significant differences were found in other secondary outcomes including anxiety, depression, general health or parental stress.

CONCLUSIONS

Social Stories™ represent a low-cost, low-burden intervention. Benefits are seen in individual socio-emotional goals but without clinically evident impact on social responsiveness, anxiety, depression, parental stress or general health.

摘要

背景

自闭症儿童可能会经历心理健康、社交和情感方面的困难。卡罗尔·格雷的“社交故事”™是一种高度个性化的干预措施,它通过简短的个性化故事提供社交信息。

方法

一项多中心实用整群随机对照试验,旨在评估“社交故事”™与常规护理相比,对4至11岁自闭症儿童的临床效果和成本效益。主要结局是随机分组6个月后由教师完成的社交反应量表-2,采用意向性分析。

试验注册

ISRCTN11634810。

结果

87所学校,共249名儿童被随机分组(干预组44所学校,129名儿童;常规护理组43所学校,120名儿童)。6个月后,干预组社交反应量表-2得分降低了1.61分(95%可信区间-4.18至0.96,p = 0.220),对于至少参加6次课程的儿童,得分降低了3.37分(校正后平均差95%可信区间-6.65至-0.10,p = 0.043)。干预组儿童比仅接受常规护理的儿童更频繁地实现其个人社会情感目标,且具有统计学意义。在包括焦虑、抑郁、总体健康或父母压力等其他次要结局方面未发现统计学显著差异。

结论

“社交故事”™是一种低成本、低负担的干预措施。在个人社会情感目标方面有获益,但对社交反应、焦虑、抑郁、父母压力或总体健康没有临床明显影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bd3/11754701/aea00e350db7/CAMH-30-4-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bd3/11754701/aea00e350db7/CAMH-30-4-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bd3/11754701/aea00e350db7/CAMH-30-4-g001.jpg

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Parent-reported social-communication changes in children diagnosed with autism spectrum disorder during the COVID-19 pandemic in the UK.
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