Lu Chao, Xiang Yun, Xu Kewei, Gao Fengrui, Zhu Shaofeng, Lou Fangfang, Liu Lu, Peng Xin
Ningbo Municipal Hospital of Traditional Chinese Medicine (TCM), Affiliated Hospital of Zhejiang Chinese Medical University, Ningbo, 315000, PR China.
Academy of Agriculture Science Research Jinhua city, Jinhua, 321017, PR China.
Poult Sci. 2025 Jan;104(1):104652. doi: 10.1016/j.psj.2024.104652. Epub 2024 Dec 10.
Tetrastigma hemsleyanum (TH) has attracted much attention for its heat clearing and detoxification effects, but whether it can become an effective feed supplement in chickens remains unclear. Herein, a total of 120 male Jinhua yellow chickens (two-mth-old) were randomly divided into into four groups (CON, TH-L, TH-M, and TH-H) for a 56-day feeding trial to explore its effects on growth performance and underlying mechanism. Results revealed that dietary TH notably increased the average daily growth (ADG), and decreased the average daily feed intake (ADFI) and feed conversion ratio (FCR) in TH-H group during 29-56 days. Meanwhile, dietary TH improved the development of duodenum and notably increased the contents of essential amino acids and flavor amino acids, while the serum oxidation stress index as well as abdominal fat deposition were not affected in Jinhua yellow chickens. Additionally, TH supplementation notably increased gut microbiota richness, then selectively increased the colonization of potential probiotics and the microbial abundance associated to amino acid synthesis and metabolic pathways in duodenum. Furthermore, qPCR analysis results preliminarily verified that dietary TH not only enhanced intestinal amino acids (rBAT and EAAT3) and peptides (PepT1 and APN) transport but also alleviated the inflammation (IL-1β, IL-6 and IFN-γ), thus thereby improved intestinal development and growth performance in Jinhua yellow chickens. These findings demonstrated that TH is a feed additive that can improve growth performance, muscle amino acids composition and intestinal development.
三叶崖爬藤（TH）因其清热排毒作用而备受关注，但它能否成为鸡的有效饲料添加剂仍不清楚。在此，总共120只两月龄雄性金华黄鸡被随机分为四组（对照组、低剂量TH组、中剂量TH组和高剂量TH组），进行为期56天的饲养试验，以探究其对生长性能的影响及潜在机制。结果显示，在29至56天期间，高剂量TH组的日粮TH显著提高了平均日增重（ADG），并降低了平均日采食量（ADFI）和饲料转化率（FCR）。同时，日粮TH改善了十二指肠的发育，并显著增加了必需氨基酸和风味氨基酸的含量，而金华黄鸡的血清氧化应激指数以及腹部脂肪沉积未受影响。此外，添加TH显著增加了肠道微生物群的丰富度，然后选择性地增加了潜在益生菌的定植以及十二指肠中与氨基酸合成和代谢途径相关的微生物丰度。此外，qPCR分析结果初步证实，日粮TH不仅增强了肠道氨基酸（rBAT和EAAT3）和肽（PepT1和APN）的转运，还减轻了炎症（IL-1β、IL-6和IFN-γ），从而改善了金华黄鸡的肠道发育和生长性能。这些发现表明，TH是一种可以改善生长性能、肌肉氨基酸组成和肠道发育的饲料添加剂。
