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迈向黑色素瘤诊断的集成成像:多光谱、高光谱和热技术综述及初步系统开发

Towards an integrated imaging for melanoma diagnosis: A review of multispectral, hyperspectral, and thermal technologies with preliminary system development.

作者信息

Oniga Maria, Sultana Alina, Alexandrescu Bogdan, Orzan Olguța

机构信息

National University of Science and Technology POLITEHNICA Bucharest, Splaiul Independenței 313, Bucharest, Romania.

National University of Science and Technology POLITEHNICA Bucharest, Splaiul Independenței 313, Bucharest, Romania.

出版信息

Comput Biol Med. 2025 Feb;185:109570. doi: 10.1016/j.compbiomed.2024.109570. Epub 2024 Dec 16.

Abstract

The diagnosis of melanoma traditionally relies on visual inspection or on the use of the dermoscope, which do not have capabilities for early and precise detection. In this review, we aimed to explore other imaging technologies that can provide non-invasive and detailed information on skin lesions, such as multispectral, hyperspectral and thermal imaging. In this regard, the systems were evaluated in terms of hardware, performance and clinical applications. Since there is currently a very big interest in developing artificial intelligence (AI) applications in dermatology, the review also focuses on analysing studies that integrated this technology with newer imaging systems. To obtain clinical validation for such systems, there is an extensive need for publicly available datasets, as the current ones are limited. Expanding and obtaining new datasets is crucial in advancing research for a more accurate melanoma diagnosis. Taking into consideration the benefits that these imaging modalities can provide if they are combined with AI, we propose a prototype that can distinguish between melanoma and its precursor, the nevus, for which the set-up, components, imaging processing pipeline and classification techniques are described. The final system benefits of the advantages provided by near infrared, thermal and visible cameras, that allow a more in-depth characterizations of melanoma for a better understanding of its behaviour, an early detection improvement and diagnostic precision.

摘要

黑色素瘤的诊断传统上依赖于目视检查或使用皮肤镜,而这些方法都没有早期精确检测的能力。在本综述中,我们旨在探索其他能够提供有关皮肤病变的非侵入性详细信息的成像技术,如多光谱、高光谱和热成像。在这方面,我们从硬件、性能和临床应用等方面对这些系统进行了评估。由于目前在皮肤病学领域开发人工智能(AI)应用的兴趣非常浓厚,本综述还着重分析了将该技术与新型成像系统相结合的研究。为了使此类系统获得临床验证,由于现有公开可用数据集有限,因此迫切需要扩充数据集。扩充并获取新数据集对于推进更准确的黑色素瘤诊断研究至关重要。考虑到这些成像模式与AI结合后所能带来的益处,我们提出了一个能够区分黑色素瘤及其前驱病变痣的原型,并描述了其设置、组件、图像处理流程和分类技术。最终系统受益于近红外、热成像和可见光相机所提供的优势,能够对黑色素瘤进行更深入的特征描述,从而更好地了解其行为,提高早期检测能力和诊断精度。

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