Khullar Poonam, Hon Jane Date, Sethi Shalini, Kim Julia, Iqbal Momin, Chavez Martin R
Department of Pathology, NYU Grossman Long Island School of Medicine, New York University Langone Hospital Long Island.
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, NYU Grossman Long Island School of Medicine, New York University Langone Hospital Long Island, Mineola, New York.
Clin Obstet Gynecol. 2025 Mar 1;68(1):119-129. doi: 10.1097/GRF.0000000000000919. Epub 2024 Dec 18.
This comprehensive review examines the effects of various infections on pregnancy, focusing on maternal symptoms, fetal outcomes, diagnostic methods, and placental pathology. The paper covers bacterial, viral, and parasitic infections, their mechanisms of transmission, clinical presentations, and histopathologic findings in the placenta. It emphasizes the importance of early detection and intervention, highlighting the challenges in diagnosis due to often asymptomatic presentations. The review also discusses the placenta's role as a protective barrier and its immune defense mechanisms against pathogens. Overall, this paper serves as a comprehensive resource for understanding the complex interplay between maternal infections, placental pathology, and fetal outcomes.
这篇综述性文章探讨了各种感染对妊娠的影响,重点关注母体症状、胎儿结局、诊断方法和胎盘病理学。该论文涵盖了细菌、病毒和寄生虫感染,它们的传播机制、临床表现以及胎盘中的组织病理学发现。它强调了早期检测和干预的重要性,突出了由于通常无症状表现而在诊断中面临的挑战。该综述还讨论了胎盘作为保护屏障的作用及其针对病原体的免疫防御机制。总体而言,本文为理解母体感染、胎盘病理学和胎儿结局之间的复杂相互作用提供了全面的资源。