Chowdhary Ramesh, V Midhula
Brånemark Osseointegration Center India, Vijaynagar, Bengaluru.
J Oral Implantol. 2025 Feb 1;51(1):27-35. doi: 10.1563/aaid-joi-D-24-00131.
The present pilot clinical trial was planned to evaluate the effect of particulate deproteinized bovine bone graft mixed with blood used as a vertical ridge augmentation material without covering with any form of collagen membrane in a tunnel pouch technique, resulting in sufficient bone formation to allow placement of dental implants with maintenance of the newly formed bone after final restoration. Eight patients (3 males and 5 females) were selected for this procedure and treated between February 2016 and December 2017. All these patients had a deficient vertical height of the posterior mandibular alveolar bone above the inferior alveolar canal. The particulate deproteinized organic bovine bone graft (Bio-Oss) mixed with blood was placed through the tunnel in the defected area and compacted firmly to form a dense pack. The average gain of alveolar bone in the first implant site immediately postoperative was 13.51 ± 0.85 and in the second implant site was 13.84 ± 0.62. Histomorphometric analysis showed that about 70.31% of the area analyzed was occupied by the vital bone, the newly formed bone, whereas only 29.69% of the residual graft remained. In the present pilot study, the deproteinized bovine bone graft placed to enhance vertical and horizontal bone gain showed positive results in regaining the bone needed to place implants and maintaining the bone around restored implants for 4 years of follow-up.
本项初步临床试验旨在评估采用隧道袋技术,将脱蛋白牛骨颗粒与血液混合用作垂直牙槽嵴增高材料,且不覆盖任何形式胶原膜的效果,以期形成足够的骨组织,以便在最终修复后植入牙种植体并维持新形成骨组织的稳定性。选取8例患者(3例男性,5例女性)接受该手术治疗,治疗时间为2016年2月至2017年12月。所有这些患者下颌后牙区牙槽骨垂直高度在牙槽神经管上方均存在不足。将脱蛋白有机牛骨颗粒移植物(Bio-Oss)与血液混合后,通过隧道置入缺损区域并紧密压实形成致密填充物。术后即刻,第一个种植位点牙槽骨平均增高13.51±0.85,第二个种植位点为13.84±0.62。组织形态计量学分析显示,所分析区域约70.31%为活性骨即新形成骨所占据,而剩余移植物仅占29.69%。在本项初步研究中,用于增加垂直和水平骨量的脱蛋白牛骨移植物在获取植入所需骨组织以及在4年随访期内维持修复后种植体周围骨组织方面显示出积极效果。