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使用脱蛋白牛骨移植材料和胶原膜进行牙槽嵴保存及延期种植体植入

Alveolar ridge preservation with deproteinized bovine bone graft and collagen membrane and delayed implants.

作者信息

Pang Chaoyuan, Ding Yuxiang, Zhou Hongzhi, Qin Ruifeng, Hou Rui, Zhang Guoliang, Hu Kaijin

机构信息

From the Department of Stomatology, State Key Laboratory of Military Stomatology, School of Stomatology, Fourth Military Medical University, Xi'an, People's Republic of China.

出版信息

J Craniofac Surg. 2014 Sep;25(5):1698-702. doi: 10.1097/SCS.0000000000000887.

Abstract

To evaluate clinically and radiographically an alveolar ridge, preservation technique with deproteinized bovine bone graft and absorbable collagen membrane and then restoration with delayed implants were done. The study included 30 patients. The trial group's sockets were filled with deproteinized bovine bone graft (Bio-Oss) and covered with absorbable collagen membrane (Bio-Gide). The control group's sockets healed without any treatment. Panoramic radiograph and computed tomography were taken immediately after graft and 3 and 6 months later to evaluate the height, width, and volume change of the alveolar ridge bone. Dental implants were inserted in all sockets at 6 months, and osseointegration condition was evaluated in the following 12 months. All sockets healed uneventfully. In the trial group, the mean (SD) height reduction of the alveolar ridge bone was 1.05 (0.24) mm at 3 months and 1.54 (0.25) mm at 6 months. The width reduction was 1.11 (0.13) mm at 3 months and 1.84 (0.35) mm at 6 months. Bone volume reduction was 193.79 (21.47) mm at 3 months and 262.06 (33.08) mm at 6 months. At the same trend, in the control group, the bone height reduction was 2.12 (0.15) mm at 3 months and 3.26 (0.29) mm at 6 months. The width reduction was 2.72 (0.19) mm at 3 months and 3.56 (0.28) mm at 6 months. Bone volume reduction was 252.19 (37.21) mm at 3 months and 342.32 (36.41) mm at 6 months. There was a significant difference in alveolar ridge bone height, width, and volume reduction in the 2 groups. The osseointegration condition had no significant difference between the 2 groups. This study suggested that the deproteinized bovine bone graft and absorbable collagen membrane were beneficial to preserve the alveolar ridge bone and had no influence on the osseointegration of delayed implant.

摘要

为了对牙槽嵴进行临床和影像学评估,采用脱蛋白牛骨移植和可吸收胶原膜的保存技术,然后植入延期种植体进行修复。该研究纳入了30例患者。试验组的牙槽窝用脱蛋白牛骨移植材料(Bio-Oss)填充,并用可吸收胶原膜(Bio-Gide)覆盖。对照组的牙槽窝不进行任何治疗任其愈合。在植入材料后即刻、3个月和6个月时拍摄全景X线片和计算机断层扫描,以评估牙槽嵴骨的高度、宽度和体积变化。在6个月时,所有牙槽窝均植入牙种植体,并在随后的12个月内评估骨整合情况。所有牙槽窝均顺利愈合。试验组中,牙槽嵴骨的平均(标准差)高度在3个月时降低1.05(0.24)mm,在6个月时降低1.54(0.25)mm。宽度在3个月时降低1.11(0.13)mm,在6个月时降低1.84(0.35)mm。骨体积在3个月时减少193.79(21.47)mm,在6个月时减少262.06(33.08)mm。对照组呈现相同趋势,骨高度在3个月时降低2.12(0.15)mm,在6个月时降低3.26(0.29)mm。宽度在3个月时降低2.72(0.19)mm,在6个月时降低3.56(0.28)mm。骨体积在3个月时减少252.19(37.21)mm,在6个月时减少342.32(36.41)mm。两组在牙槽嵴骨高度、宽度和体积减少方面存在显著差异。两组在骨整合情况方面无显著差异。本研究表明,脱蛋白牛骨移植材料和可吸收胶原膜有利于保存牙槽嵴骨,且对延期种植体的骨整合无影响。

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